new advances in mass spectrometry-based proteomics technology are having amajor impact on our understanding of how human spermatozoa acquire their capacity for fertilization. a complete analysis of the proteins found in the human spermatozoa is essential for understanding the events leading up to, and including, fertilization and early embryo development. in this short review, we have collected...

aim : evaluation of biological characteristics of 13 identified proteins of patients with cirrhotic liver disease is the main aim of this research.   background : in clinical usage, liver biopsy remains the gold standard for diagnosis of hepatic fibrosis. evaluation and confirmation of liver fibrosis stages and severity of chronic diseases require a precise and noninvasive biomarkers. since the...

All tools in the DAVID Bioinformatics Resources aim to provide functional interpretation of large lists of genes derived from genomic studies. The newly updated DAVID Bioinformatics Resources consists of the DAVID Knowledgebase and five integrated, web-based functional annotation tool suites: the DAVID Gene Functional Classification Tool, the DAVID Functional Annotation Tool, the DAVID Gene ID ...

All tools in the DAVID Bioinformatics Resources aim to provide functional interpretation of large lists of genes derived from genomic studies. The newly updated DAVID Bioinformatics Resources consists of the DAVID Knowledgebase and five integrated, web-based functional annotation tool suites: the DAVID Gene Functional Classification Tool, the DAVID Functional Annotation Tool, the DAVID Gene ID ...

Computational Biology & Bioinformatics) Characterization of Gene Interaction and Assessment of LD Matrix Measures for the Analysis of Biological Pathway Association by David R. Crosslin Department of Computational Biology & Bioinformatics Duke University

Analysis and Redesign of Protein-Protein Interactions: A Hotspot-Centric View by Curtis James Layton Program in Computational Biology and Bioinformatics Duke University Date:_______________________ Approved: ___________________________ Homme Hellinga, Supervisor ___________________________ David Beratan ___________________________ Terrence Oas ___________________________ Weitao Yang ___________...

The Arthur M. Sackler Colloquium of the National Academy of Sciences, "Frontiers in Bioinformatics: Unsolved Problems and Challenges," organized by David Eisenberg, Russ Altman, and myself, was held October 15-17, 2004, to provide a forum for discussing concepts and methods in bioinformatics serving the biological and medical sciences. The deluge of genomic and proteomic data in the last two de...

1 Single-cell transcriptome analysis of fish immune cells 1 provides insight into the evolution of vertebrate immunity 2 Santiago J. Carmona, Sarah A. Teichmann, Lauren Ferreira, Iain C. 3 Macaulay, Michael J.T. Stubbington, Ana Cvejic, David Gfeller 4 5 6 Ludwig Center for Cancer Research, University of Lausanne, Lausanne, Switzerland 7 Swiss Institute of Bioinformatics (SIB), 1015 Lausanne, ...

Correspondence to: Marc S. Halfon; Department of Biochemistry; Center of Excellence in Bioinformatics; State University of New York at Buffalo; 140 Farber Hall, 3435 Main Street; Buffalo, New York 14214-3000 USA; Tel.: 716.829.8126; Fax: 716.829.2725; Email: [email protected]/ David N. Arnosti; Department of Biochemistry and Molecular Biology; Michigan State University; East Lansing, Michiga...