Introduction: The functional effects of orexin-B on the calcium spikes and excitability of the neuronal soma membrane of garden snail, Helix aspersa were studied. Methods: Conventional intracellular recording, under the current clamp conditions was performed to examine the effects of orexin-B on the configuration and electrophysiological properties of calcium spikes. Results: Application o...

HIGHLIGHTS Ischemia-reperfusion triggers acute kidney injury due to reactive oxygen species. Quercetin is an antioxidant flavonoid that modulate the Rennin-Angiotensin System. prevents tubular cell death, oxidation, and mitochondrial depolarization. interacts with angiotensin AT1 receptor.

We report on large-scale simulations of intrachain exciton dynamics in poly(para-phenylenevinylene). Our theoretical model describes Frenkel coupling to both fast, quantized C–C bond vibrations and slow, classical torsional modes. also incorporate system–bath interactions. The is simulated using the time evolution block decimation method, which avoids failures Ehrenfest approximation describe d...