In the title mol-ecular salt, C(6)H(6)NO(2) (+) (.)C(4)H(3)O(4) (-), the 2-carb-oxy-pyridinium cation is essentially planar with a maximum deviation of 0.003 (3) Å. In the crystal, adjacent cations and anions are linked by an extensive system of weak N-H⋯O, O-H⋯O and C-H⋯O inter-actions, forming a layer parallel to the ab plane.

Chlorpheniramine maleate-paracetamol-caffeine tablet formulation is one of the common over-the-counter drugs used for the treatment of cold and cough. A reversed-phase high-performance liquid-chromatography method has been successfully developed for the simultaneous determination of chlorpheniramine maleate, paracetamol and caffeine in a drug formulation. The RP-HPLC method employed a Phenomene...

Enalapril maleate is used in the treatment of hypertension and angina pectoris. It shows low bioavailability due to high hepatic first pass metabolism. Hence the present work was undertaken to formulate mucoadhesive buccal films of enalapril maleate with an objective to improve therapeutic efficacy, patient compliance and the bioavailability. In the present study ten formulations of mucoadhesiv...

In the title compound, C(4)H(8)N(3)O(+)·C(4)H(3)O(4) (-), the cations and anions are linked through N-H⋯O hydrogen bonds making a ionic pair with an R(2) (2)(8) ring motif. These ionic pairs are further connected through another N-H⋯O hydrogen bond, leading to an R(6) (6)(16) ring motif around the inversion centres of the unit cell. These approximately planar aggregates are further connected th...

Dr. R. Peces, Servicio de Nefrologia, Hospital Covadonga, Celestino Villamil s/n, E-33006 Oviedo (Spain) Dear Sir, Intravenous methylprednisolone is currently used before transplantation as well as for the treatment of acute rejection episodes. Hypersensitivity to methylprednisolone is extremely rare and the reported cases were mostly in atopic or asthmatic patients [1–7]. Among them, only 2 ca...

A new cyclohexyl based fluorescent anion receptor, is able to recognize maleate versus fumarate both as their TMA salts.

When added to the culture medium of human liver cell lines, perhexiline maleate induced formation of numerous myeloid bodies containing unicentric or multicentric smooth membranes within a few days. The nine lysosomal enzyme activities studied, except for beta-galactosidase which decreased, remained unchanged. These results indicate that on cultured human liver cells perhexiline maleate has an ...

In the title coordination polymer, {[Sm(2)(C(4)H(2)O(4))(3)(H(2)O)(6)]·6H(2)O}(n), the Sm(III) ion is nine-coordinated by four O atoms from three different maleate ligands, two O atoms from one fumarate ligand and three O atoms from three water mol-ecules. The fumarate ligand lies on an inversion center. Adjacent Sm(III) ions are bridged by the maleate and fumarate ligands, forming a layer para...