patients presenting with nephrotic syndrome with or without nephritic illness rarely come across with the diagnosis of ‘c1q nephropathy’. this entity is purely diagnosed with the help of immunofluorescence like iga nephropathy. clinical presentation is heterogenous, ranging from nephrotic range proteinuria to sub-nephrotic state; and with or without hematuria / renal insufficiency. similarly, t...

The realization of personalized medicine through human induced pluripotent stem cell (iPSC) technology can be advanced by transcriptomics, epigenomics, and bioinformatics that inform on genetic pathways directing tissue development and function. When possible, population diversity should be included in new studies as resources become available. Previously we derived replicate iPSC lines of Afri...

We will present the architecture of an intermediate processing layer for large information systems. Tasks assigned to that layer include managing access to information resources as databases, knowledge bases, sensor-based processing systems, message processing systems, and systems that project into the future, as simulations can do. To convert the data into information, it has to be abstracted,...

The main theme of this paper is culture justice, which is the new paradigm of culture development in the 21 century. The 21 century is characterized primarily by globalization and by the rapid development of science and technology. Confronted by the opportunities and challenges offered by these changes, different countries and people with different cultural traditions will make important judgme...

NEWS NEWS What do cerebellar Purkinje cells, working myocardium, skeletal muscle myocytes and cochlear inner hair cells (IHCs) have in com-mon? Their high-voltage activated (HVA) Ca 2+ currents are mediated almost exclusively by a single calcium channel type: Cav2.1 (P-type) in Purkinje cells, Cav1.2 L-type in the heart, Cav1.1 in skeletal muscle and Cav1.3 in IHCs. In most other electrically e...