BACKGROUND AND OBJECTIVES This study compares donor quality of life (QOL) with extirpative (simple or radical) patients' QOL after laparoscopic nephrectomy and analyzes factors predictive of mental QOL for donors. METHODS One hundred one donors and 48 extirpative laparoscopic nephrectomy patients filled out the SF-36v2 form at pre- and postoperative visits, and scores were transformed to norm...

([email protected]). The authors are grateful to Claudio Montenegro for assistance with aid data, and to Ritva Reinikka and Bill Shaw for valuable discussions and comments. The conclusions of this paper are not intended to represent the views of the World Bank, its Executive Directors, or the countries they represent.

The contributions of donor kidney quality (partially determined by donor age), allograft rejection, and calcineurin inhibitor nephrotoxicity on the progression of histologic damage of renal allografts are not completely defined. Moreover, the determinants of individual susceptibility to calcineurin inhibitor nephrotoxicity are not known but may include variability in drug transport and metaboli...

Primary graft dysfunction is an important cause of morbidity and mortality after cardiac transplantation. Donor brain stem death (BSD) a significant contributor to donor heart primary dysfunction. There remain substantial gaps in the mechanistic understanding peritransplant One these metabolism metabolic function. The healthy “omnivore,” capable utilizing multiple sources nutrients fuel its eno...

Transfusion of blood and blood preparations is indispensible in modern medicine, and the processes of delivering a transfusion to a patient provide additional opportunity for risk, despite the remarkable progress. A spectrum of blood-borne infectious agents is transmitted through transfusion of infected blood donated by apparently healthy and asymptomatic blood donors. The diversity of infectio...

OBJECTIVE To review a single-institution 6-year experience with laparoscopic live donor nephrectomy detailing the technical modifications, clinical results, as well as the trends in donor and recipient morbidity. SUMMARY BACKGROUND DATA Since 1995, laparoscopic donor nephrectomy has had a significant impact on the field of renal transplantation, resulting in decreased donor morbidity, without...

BACKGROUND Transfusion of plasma is a basic treatment for complex coagulopathies as well as in major blood loss. Early transfusion of plasma after trauma with major hemorrhage has been recommended by retrospective studies. However, the use of plasma is often hampered by the need to maintain a cold chain and the time needed for thawing fresh-frozen plasma (FFP). With freeze-dried (lyophilized) p...