BACKGROUND/AIMS We investigated the prevalence and relationship of peptic ulcer disease and Helicobacter pylori infection to liver cirrhosis. METHODS We examined 288 patients with liver cirrhosis, 322 patients with non-ulcer dyspepsia, and 339 patients with peptic ulcer disease. Rapid urease test and Wright-Giemsa staining were used for diagnosis of H. pylori infection. RESULTS The prevalen...

BACKGROUND The prevalence rate of gastric infections caused by Helicobacter pylori is different in between as well as within various countries, including Iran. OBJECTIVES This study was aimed to evaluate the prevalence of H. pylori in Iranian adult patients with dyspepsia. PATIENTS AND METHODS A total of 548 patients with dyspepsia referred to Namazi Hospital, a referral center for gastroin...

The role of fibreoptic upper gastrointestinal endoscopy as the primary investigation in Malaysians presenting with dyspepsia was studied in 1119 patients. Five hundred and sixty-two of the examinations (50 percent) were normal. Females below 40 years of age were very likely to have normal endoscopies. Peptic ulcer was seen in 21 percent of patients while visual evidence of gastric or duodenal m...

Proton pump inhibitors are the first-line treatment for reflux esophagitis. Because severe reflux esophagitis has very low prevalence in Japan, little is known about the effectiveness of proton pump inhibitors in these patients. This prospective multicenter study assessed the effectiveness of proton pump inhibitors for severe reflux esophagitis in Japan. Patients with modified Los Angeles grade...

OBJECTIVE To assess the frequency of common mental disorders among diagnosed functional dyspepsia patients. METHODS A case-control study with 150 cases of functional dyspepsia (FD) and 150 healthy controls were recruited from Gastroenterology Clinic at the Aga Khan University Hospital Karachi from 1st March 2009 through 31st August 2009. Urdu version of WHO-developed Self-Reporting Questionna...

Introduction: Helicobacter pylori (H. pylori) is suggested to play a role in dyspepsia. The aim of this study was to assess the prevalence of H. pylori, in dyspeptic patients. Methods: This cross-sectional study was conducted on 850 patients with dyspepsia in Iran (2006-2007). The patients were selected using convenience sampling method. Data was collected using ROME III criteria questionnaire...

BACKGROUND The benefits of the Helicobacter pylori test-and-treat strategy are attributable largely to the cure of peptic ulcer disease while limiting the use of endoscopy. AIM To reappraise the test-and-treat strategy and empirical proton pump inhibitor therapy for the management of uninvestigated dyspepsia in the light of the decreasing prevalence of H. pylori infection, peptic ulcer diseas...

Helicobacter pylori (H. pylori) is one of the most common human bacterial infections with prevalence rates between 10-80% depending upon geographical location, age and socioeconomic status. H. pylori is commonly found in patients complaining of dyspepsia and is a common cause of gastritis. During the course of their infection, people living with HIV (PLHIV) often have a variety of gastrointesti...

Functional dyspepsia represents a heterogeneous group of gastrointestinal disorders marked by the presence of upper abdominal pain or discomfort. Although its precise definition has evolved over the last several decades, this disorder remains shrouded in controversy. The symptoms of functional dyspepsia may overlap with those of other functional bowel disorders including irritable bowel syndrom...

OBJECTIVE This study evaluated Helicobacter pylori eradication therapy in terms of symptomatic response in patients with functional dyspepsia. On the other hand, we analyzed the importance of histologic findings as a predictor of treatment response. In particular, we studied whether antral gastritis (which is associated with peptic ulcer) may predict a greater symptomatic response to Helicobact...