concrete is one of the most utilized construction materials in the world. nowadays, nano silicate usage due to its special property attracted considerable attention. on this basis, studying its environmental functions is an essential issue. accordingly, the behavior of normal concrete and the one with nano silicate were compared via taking advantage of life cycle assessment (lca) method in this...

2.5.1 Study quality assessment and bias 2 2.5.2 Bias and quality assessment 2 2.5.3 Quality threshold for study selection 4 2.5.4 Development of quality assessment instruments 6 2.5.5 Quality assessment of effectiveness studies 8 2.5.6 Quality assessment of test accuracy studies 11 2.5.7 Quality assessment of qualitative research 12 2.5.8 Quality assessment of economic evaluations 13 2.5.9 Key ...

OBJECTIVES To identify methodological research on the incorporation of adverse effects in economic models and to review current practice. DATA SOURCES Major electronic databases (Cochrane Methodology Register, Health Economic Evaluations Database, NHS Economic Evaluation Database, EconLit, EMBASE, Health Management Information Consortium, IDEAS, MEDLINE and Science Citation Index) were search...

OBJECTIVES The aim of this study was to explore whether wealth effects of health interventions, including productivity gains and savings in other sectors, are considered in resource allocations by health technology assessment (HTA) agencies and government departments. To analyze reasons for including, or not including, wealth effects. METHODS Semi-structured interviews with decision makers an...

OBJECTIVE Although Markov cohort models represent one of the most common forms of decision-analytic models used in health care decision-making, correct implementation of such models requires reliable estimation of transition probabilities. This study sought to identify consensus statements or guidelines that detail how such transition probability matrices should be estimated. METHODS A litera...

A common criticism of the pharmaceutical industry is that it fails to achieve transparency [1, 2]. To allay concerns, the industry needs to collaborate openly with stakeholders to make medicines widely available and affordable—this will mean companies need to address some of their practices [1, 3, 4]. We suggest that an important practice to address is the presentation of health economic models...

Sugammadex 16 mg kg⁻¹ can be used for the immediate reversal of neuromuscular block 3 min after administration of rocuronium and could be used in place of succinylcholine for emergency intubation. We have systematically reviewed the efficacy and cost-effectiveness and made an economic assessment of sugammadex for immediate reversal. The economic assessment investigated whether sugammadex appear...

Socio-economic considerations are included in the regulatory frameworks on genetically modified organisms (GMOs) of many countries. This is a reflection of an increasing interest in and recognition of the necessity to consider a broader range of issues when conducting a GMO risk assessment. At the same time, there are discussions about how socio-economic considerations can be identified and how...