نتایج جستجو برای: electrophysiological parameters
تعداد نتایج: 604158 فیلتر نتایج به سال:
Background Pyruvate, as an end-product of glycolysis, might influence the electrophysiological parameters of the heart by several mechanisms: Pyruvate enhances the phosphorylating potency of the cytosol; it can facilitate the reduction of inorganic phosphate and finally can influence the cytoplasamatic redox state by decreasing the H+ concentration. According to the literature, pyruvate enhance...
OBJECTIVE We aimed to establish whether multi-nerve testing with a point-of-care nerve conduction device could be used to diagnose diabetic sensorimotor polyneuropathy. RESEARCH DESIGN AND METHODS A total of 72 consecutive patients with diabetes underwent a full neurological examination and a concurrent evaluation for nine standard electrophysiological parameters using conventional nerve cond...
Cardiac arrhythmias are increasingly being treated using ablation procedures. Development of fast electrophysiological models and estimation of parameters related to conduction pathologies can aid in the investigation of better treatment strategies during Radio-frequency ablations. We present a fast electrophysiological model incorporating anisotropy of the cardiac tissue. A global-local estima...
The electrophysiological properties of subendocardial Purkinje fibers surviving in myocardial infarcts were studied with intracellular microelectrodes in isolated superfused preparations and correlated with subsequent light and electron microscopic studies. Transmembrane action potentials could always be recorded from one or two cell layers of subendocardial Purkinje fibers in infarcted regions...
BACKGROUND Hematopoietic progenitor cells (HPCs) can improve cardiac function after myocardial infarction. However, occurrence of arrhythmias is a potential limitation of cell therapy. In this study, we investigated the cardiac electrophysiological properties of ex vivo expanded HPCs, generated by beta-catenin gene transfer, after transcoronary delivery in a murine model of ischemia/reperfusion...
Following acute traumatic brain injury (TBI), timely transport to a hospital can significantly improve the prognosis for recovery. There is, however, a dearth of quantitative biomarkers for brain injury that can be rapidly acquired and interpreted in active, field environments in which TBIs are frequently incurred. We explored potential functional indicators for TBI that can be noninvasively ob...
BACKGROUND Investigation of neural circuit functioning often requires statistical interpretation of events in subthreshold electrophysiological recordings. This problem is non-trivial because recordings may have moderate levels of structured noise and events may have distinct kinetics. In addition, novel experimental designs that combine optical and electrophysiological methods will depend upon...
Introduction: The present study is aimed to evaluate electrophysiological remodeling of atrioventricular (AV) node and ventricular conduction during experimental atrial fibrillation (AF) model in isolated heart of cirrhotic rats. Methods: Cirrhosis-induced electrophysiological remodeling was evaluated in 24 isolated retrogradely perfused rat hearts in 2 groups (control and cirrhotic). Cirrho...
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