INTRODUCTION Coverage of bone grafts is very important in reconstructive surgery. In edentulous alveolar ridges this coverage is particularly important for supporting dental prostheses. Here we present the case of a patient with a large deficient maxillary anterior region that was reconstructed with a bilateral palatal submucosal periosteal connective tissue flap: a soft tissue reserve for uppe...

Extracellular Matrix (ECM) is the biologically active connective framework extending between cells; the composition of the ECM contributes significantly to wound healing, cell proliferation, cell mobility, and cell differentiation [1]. ECM occurs in two basic forms in animal tissues: stromal matrix and basement membrane [2]. The basement membrane is a thin layer of ECM located on the basolatera...

Introduction: A single incision palatal harvest technique was applied to minimize the size of the palatal wound and to allow for primary closure of the donor site, which may result in reduced postoperative discomfort. Aim: This case presentation describes the use of a coronally positioned flap with subepithelial connective tissue graft using a single incision technique for the treatment of dent...

Cosmetic procedures have become an integral part of periodontal treatment. One of the commonly used esthetic periodontal procedures is coverage of denuded roots. The recession of gingiva is increasingly becoming a more prominent condition in the oral health of many patients and should be treated at its earliest detection. The multi-factorial etiology, decision modality, and current trends follo...

We have previously demonstrated that keratinocyte-specific forkhead box O1 (FOXO1) deletion interferes with keratinocyte migration in normal skin wounds. However it has an opposite effect in diabetic skin wounds, significantly improving the healing response. In addition we found that skin epithelium regulates connective tissue healing mediated by FOXO1, which is strongly associated with wound a...

BACKGROUND A coronally advanced flap with subepithelial connective tissue graft is the gold standard surgical treatment of gingival recessions, since it offers a higher probability of achieving complete root coverage compared with other techniques. However, optimum short- and middle-term clinical results have also been obtained with coronally advanced flaps alone. The aim of the present study w...

BACKGROUND The aim of this clinical trial study was to clinically evaluate the use of enamel matrix protein derivative combined with the coronally positioned flap to treat gingival recession compared to the subepithelial connective tissue graft by a new method to obtain denuded root surface area. MATERIALS AND METHODS Thirteen patients, each with two or more similar bilateral Miller class I o...