In this article, we propose a new distributed sensors-based multi-target geolocation and tracking technique. The proposed technique is joint time-of-arrival (TOA) direction-of-arrival (DOA) factor graph (FG) for (FG-GE), which further combined with another FG extend Kalman filtering (FG-GE-EKF) tracking. Two-dimensional (2D) three-dimensional (3D) scenarios are considered. the FG-GE part, senso...

A new approach termed Adaptive Solvent-Scaling (AdSoS) is introduced for performing simulations of a solute embedded in fine-grained (FG) solvent region itself surrounded by coarse-grained (CG) region, with continuous FG ? CG switching the resolution across buffer layer. Instead relying on distinct model, AdSoS scheme based models defined dimensional scaling factor s, accompanied an s-dependent...

The effect of flaxseed gum (FG) on the rheological and nonlinear stress response behaviors of mixed soy protein isolate (SPI)-flaxseed gum (FG) dispersions were studied. Results showed that the viscosity of the SPI-FG mixed dispersions increased significantly with increase in the FG concentration. Both the shear stress and the apparent viscosity values as a function of shear rate were fitted we...

M ONOLITHIC piezoelectric materials (PZTs) have been widely used as distributed sensors and actuators for developing smart structures with self-monitoring and selfcontrolling capabilities [1–10]. However, their major drawback is low control authority as the magnitude of their electromechanical coefficients is very small. The situation can be improved by using an active constrained layer damping...

Inflammation-induced vascular endothelial dysfunction can allow plasma proteins to cross the vascular wall, causing edema. Proteins may traverse the vascular wall through two main pathways, the paracellular and transcellular transport pathways. Paracellular transport involves changes in endothelial cell junction proteins, while transcellular transport involves caveolar transcytosis. Since both ...

Nucleocytoplasmic transport has been the subject of a large body of research in the past few decades. Recently, the focus of investigations in this field has shifted from studies of the overall function of the nuclear pore complex (NPC) to the examination of the role of different domains of phenylalanine-glycine nucleoporin (FG Nup) sequences on the NPC function. In our recent bioinformatics st...

Entropy guards pore T he rapid fl uctuations of fl exible FG repeat–containing nucleoporins (FG Nups) form an entropic barrier to would-be entrants into the nuclear pore complex (NPC), according to Roderick Lim (University of Basel, Switzerland) and colleagues. FG Nups, which consist of large natively unfolded domains, are the pore’s gatekeepers—they keep out proteins that are not bound to tran...

The origin of platelet alpha-granule fibrinogen (Fg), whether from endogeneous synthesis or exogeneous derivation, remains unknown. Although Fg biosynthesis by megakaryocytes (MK) has been suggested, recent studies have demonstrated that certain alpha-granular proteins originate primarily from plasma. To study the origin of alpha-granule Fg, platelet-associated Fg was measured by ELISA and West...

Nucleoporins with phenylalanine-glycine repeats (FG Nups) function at the nuclear pore complex (NPC) to facilitate nucleocytoplasmic transport. In Saccharomyces cerevisiae, each FG Nup contains a large natively unfolded domain that is punctuated by FG repeats. These FG repeats are surrounded by hydrophilic amino acids (AAs) common to disordered protein domains. Here we show that the FG domain o...