Granulomatous angiitis of the central nervous system occurred in a 43-year-old male presenting with recurrent intracerebral hemorrhage confirmed by computed tomography. A surgical specimen obtained at hematoma removal revealed granulomatous angiitis. Systemic investigation found no underlying cause for the hemorrhage. Although the incidence is very low, this condition should be considered in ca...

A 42-year-old woman presented gradual development of hypersomnia and memory disturbance. T2-weighted and FLAIR MRI scans revealed a high intensity abnormality in the hypothalamus. Stereotactic brain biopsy specimen revealed prominent infiltration of the lymphocytes in the vessel walls. Since there was no evidence of systemic angiitis, the diagnosis of isolated angiitis of the CNS (IAC) was made...

A 24-year-old woman with slowly progressive altered mental status and fevers was found to have multiple brain mass lesions. A characteristic branching vascular pattern on T2* MRI (figure 1D) was key to identifying these mass lesions as vascular in origin. CSF was inflammatory and serologic testing supported the diagnosis of systemic lupus erythematosus with concomitant CNS angiitis affecting de...

This paper records a patient of Osler's, who showed many features compatible with the Churg-Strauss syndrome of allergic granulomatous angiitis to be described 50 years later.

BACKGROUND AND OBJECTIVE: Primary angiitis of the central nervous system (PACNS) is an inflammatory vasculitis with very low frequency and prevalence. It is not clear why the inflammatory process of this disease is limited to cerebrovascular disease without systemic manifestations. A case of primary angiitis of the central nervous system with cerebrovascular manifestations is reported here.  C...

Zusammenfassung Die primäre Angiitis des Zentralnervensystems ist eine sehr seltene Erkrankung, welche durch entzündliche Infiltration der Gefäßwände von mittleren und kleinen Gefäßen ausschließlich im Zentralnervensystem, vorwiegend Gehirn, gekennzeichnet ist. Klinisch radiologisch kann sich die Erkrankung äußerst vielgestaltig präsentieren stellt daher besondere diagnostische Herausforderung ...