نتایج جستجو برای: fshr
تعداد نتایج: 474 فیلتر نتایج به سال:
Endometriosis is determined by genetic factors, and the prevalence of genetic polymorphisms varies greatly depending on the ethnic group studied. The objective of this study was to investigate the relationship between single nucleotide polymorphisms (SNPs) of 9 genes involved in estrogen biosynthesis and metabolism and the risks of endometriosis. Three hundred patients with endometriosis and 33...
Post-natal testicular development is dependent on gonadotrophin and androgen stimulation. Follicle stimulating hormone (FSH) acts through receptors (FSHR) on the Sertoli cell to stimulate spermatogenesis while androgens promote testis growth through receptors (AR) on the Sertoli cells, Leydig cells and peritubular myoid cells. In this study we have examined the effects on testis development of ...
Women of reproductive ages are varies in their responses to exogenous FSH stimulations. The difference of FSHR genotype due to the polymorphisms in exon 10 is one of its significant factors. To know further whether the core promoter of FSHR is also polymorphic and to know whether those polymorphisms influence the promoter activity, we did polymorphism screening of FSHR promoter to 262 women und...
The gonadotropin known as follicle-stimulating hormone (FSH) plays a key role in regulating reproductive processes. Physiologically active FSH is a glycoprotein that can accommodate glycans on up to four asparagine residues, including two sites in the FSHα subunit that are critical for biochemical function, plus two sites in the β subunit, whose differential glycosylation states appear to corre...
BACKGROUND Single-nucleotide polymorphisms (SNPs) in the follicle stimulating hormone receptor (FSHR) gene are associated with PCOS. However, their relationship to the polycystic ovary (PCO) morphology remains unknown. This study aimed to investigate whether PCOS related SNPs in the FSHR gene are associated with PCO in women with PCOS. METHODS Patients were grouped into PCO (n = 384) and non-...
با توجه به افزایش شیوع ناباروری که حدود 15% زوج ها را در سنین باروری شامل می شود اهمیت تکنیک های کمک باروری پر رنگ تر می شود همچنین دسته بزرگی از زنان pcos برای باروری از این تکنیک ها استفاده می کنند. ابداع پروتکل های موثرتر برای تحریک مناسب تخمک گذاری موفقیت این تکنیک ها را تضمین می کند، اساس کار این تکنیک ها استفاده از هورمون های اگزوژن به خصوص fsh برای تحریک تخمک گذاری است. fsh اثر خود را بر...
چکیده رشد و نمو فولیکول ها توسط هورمون های باروری، به ویژه هورمون محرک فولیکولی تنظیم می شود. این هورمون و گیرنده اش نقش مهمی را در توسعه فولیکولی و تنظیم استروئیدوژنز بازی می کند. اینهیبین به عنوان یک عامل ضروری در تنظیم ترشح fsh در پستانداران مختلف نقش بازی می کند. این جایگاه های ژنی با توجه به نقش آنها در تولید مثل می توانند به عنوان مارکرهای احتمالی برای صفات تولید مثلی در حیوانات اهلی به ...
Ovarian follicle selection is an important process impacting the laying performance and fecundity of hens, and is regulated by follicle-stimulating hormone (FSH) through binding to its receptor [follicle-stimulating hormone receptor (FSHR)]. In laying hens, the small yellow follicle (6-8 mm in diameter) with the highest expression of FSHR will be recruited into the preovulatory hierarchy during...
Growth factors such as bone morphogenetic proteins 6, 7, 15, and two isoforms of transforming growth factor-beta (BMP6, BMP7, BMP15, TGFB1, and TGFB2), and insulin-like growth factor system act as local regulators of ovarian follicular development. To elucidate if these factors as well as others candidate genes, such as estrogen receptor 1 (ESR1), growth differentiation factor 9 (GDF9), follicl...
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