OBJECTIVE To determine whether garlic extract therapy is efficacious and safe in children with hypercholesterolemia. DESIGN Randomized, double-blind, placebo-controlled clinical trial. SETTING Specialized pediatric lipid disorders ambulatory clinic. PARTICIPANTS Thirty pediatric patients, aged 8 to 18 years, who had familial hyperlipidemia and a minimum fasting total cholesterol level gre...

OBJECTIVE The present study was hypothesized to investigate the beneficial effects of fresh, aged, and cooked garlic extracts on blood glucose and memory of diabetic rats induced by streptozocine (STZ). MATERIAL AND METHODS Diabetes was induced by an intraperitoneal injection of STZ (60 mg/kg body weight). An oral dose of 1000 mg/kg of each garlic extract was given daily for 4 weeks after dia...

The hypotensive effect of garlic has been well-documented in human subjects and animals. Since endothelial activity regulates vascular reactivity in physiological and pathophysiological conditions, the aim of the present study was to investigate the effect of garlic on endothelium-dependent and independent relaxation of rat aorta for elucidation of mechanism of the garlic anti-hypertensive effe...

introduction: the most important virulence factor of brucella is related to its capability of intraphagocytic survival. brucella with this ability,causes persistant infection in host. garlic extract, because of has organosulfur compounds such as allicin, has antimicrobial activity. the aim of this study was to investigate the effect of garlic choloroformic extract on intramacrophage brucella sp...

Background & Aims: There are several reports about anti-oxidant effects of garlic in the literature. In this study the effect of garlic alcoholic-water extract on the treatment of lead-induced toxicity in kidney of neonatal rat and the protective effect of garlic alcoholic water extract on body and kidney weight and also kidney tissue were investigated. Method: Neonatal rats were divided in...

The purpose of this study was to analyze the indolic, phenolic, and fatty acid content and antioxidant activity of garlic sprouts growing in the dark and in the daylight. The pro- or anti-inflammatory properties of the garlic sprout extract were investigated by evaluating the cyclooxygenase-2 (COX-2), prostaglandin E synthase (cPGES), glutathione S transferase (GSTM1), nuclear factor NF-κB, per...

in this study, the effect of garlic extract on the growth performances ( body weight increase (bwi), specific growth rate (sgr), condition factor (cf), final length (fl) and weight (fw)), feed indices (feed conversion rate (fcr), protein efficiency ratio (per), protein production ratio (ppr)) and body composition (protein, fat, moisture and ash) of mugil cephalus larvae were studied in four tre...