Magnetic Resonance (MR) imaging has not become popular for staging of gastric carcinoma because of a number of limitations, including motion artifacts, lack of a stable contrast medium, and the high cost. However, continuous technical improvements have been made in MR imaging of the abdomen, thereby reducing motion artifacts and improving image quality. These improvements include breath-hold fa...

Gastric carcinoma is reported to be more frequent in geographical areas where diets are either iodine-deficient or iodine-excessive. Reports have also shown an association between thyroid diseases and some of the risk factors for gastric carcinoma. We investigated the frequency of thyroid disorders in 61 patients with gastric carcinoma compared with 55 healthy control subjects. Thyroid health w...

The expression of epidermal growth factor (EGF), epidermal growth factor receptor (EGFR), transforming growth factor alpha (TGF alpha), and of c-erbB-2 was immunohistochemically investigated in resected gastric carcinoma (in 39 cases of superspreading type and in 11 cases of penetrating type), to understand the differential biological features of these two types of gastric carcinoma. EGF, EGFR ...

Most cervical adenocarcinomas currently are HPV related. With increasing use of vaccine, the prevalence related carcinomas may reduce & there might be relative increase in occurrence non carcinomas. Gastric variant adenocarcinoma is one such HPV-independent carcinoma and recognized as distinct entity by WHO 2014. A spectrum benign, premalignant malignant endocervical lesions showing gastric...

Reduced expression level of p27, a cyclin-dependent kinase inhibitor, is associated with high aggressiveness and poor prognosis of various malignant tumors, including gastric carcinoma. S-phase kinase-associated protein 2 (Skp2), a member of the F-box family of substrate-recognition subunits of Skp1-Cullin-F-box ubiquitin-protein ligase complexes, is necessary for p27 ubiquitination and degrada...

BACKGROUND CD10 is a cell surface metalloproteinase expressed by a variety of normal cell types, including lymphoid precursor cells, germinal center B lymphocytes and some epithelial cells. Although accumulating data indicate that CD10 expression by stromal cells is involved in colorectal carcinogenesis and it is a novel prognostic factor in breast carcinoma, CD10-positive stromal cells and the...

Gastric carcinoma is the third commonest cause of cancer death in men, worldwide. The overall incidence of gastric cancer has declined rapidly over the recent few decades, yet there are marked geographic variations of this, with extremely high incidence in Eastern Asia, the Andean regions of South America, and Eastern Europe. Whilst it is not commonly seen throughout Africa, gastric carcinoma i...

OBJECTIVE Variable uptake of 2-deoxy-2-[18F]fluoro-D-glucose (FDG) has been noticed in positron emission tomography (PET) studies of gastric carcinoma patients, with low uptake occurring especially in some particular histological subtypes and early carcinomas. But this phenomenon has not been adequately explained. The aim of the present study is to clarify FDG uptake in gastric carcinomas espec...

In the United States, early diagnosis and cure of gastric carcinoma remain elusive. Patients with this disease commonly have gastrointestinal symptoms that often go unexplained. Physicians give gastric carcinoma a low priority in their differential diagnosis and are unaware of the risk factors patients may have. Patients may have a normal upper gastrointestinal series, and fiberoptic gastroscop...

OBJECTIVE The purpose of this work was to analyze the relationships between the expression status of Lysosomal-associated protein transmembrane-4 beta 35 (LAPTM4B-35) in cancerous tissues and clinicopathological characteristics and prognosis of the patients with gastric carcinoma (GC). METHODS The GC samples from 157 patients in a discovery cohort and 148 patients in a testing cohort with fol...