Background: Cancer is the priority of the World Health Organization (WHO) and a serious challenge in death of human untimely. Assessment of social and physiological risk factors in gastric carcinoma patients can reveal the reasons of high prevalence gastric carcinoma in Sanandaj city. Methods: In a descriptive cross-sectional study, the variables of sex, age, education, occupation and active H...

objective(s): expression of her2 in gastric carcinoma has direct prognostic and therapeutic implications in patient management. the aim of this study is to determine whether a relationship exists between standardized uptake value (suv) and expression of her2 in advanced gastric carcinoma. methods: we analyzed the 18f-fdg pet/ct results of 109 patients that underwent gastrectomy for advanced gas...

background the process of neoplastic transformation in the stomach has been reported to be associated with decreased expression of normal mucins of the gastric mucosa and denovo expression of mucins that are normally expressed in other organs. this association may be used as a means to bring new insights into biologic behavior and genetic pathways in the development of gastric cancer. there are...

cancer starts with a change in one single cell. this change may be initiated by external agents and genetic factors. cancer is a leading cause of death worldwide and accounts for 7.6 million deaths (around 13% of all deaths) in 2008. lung, stomach, liver, colon and breast cancer cause the most cancer deaths each year. in this review, different aspects of gastric cancer; including clinical, path...

conclusions according to this observation, another factor such as oncogenes activity may cause cancer in samples but ct genotype of mthfr can be considered as an effective factor in creating cancer. results methylation status of e-cadherin gene numbers of methylated cases in the cancer group were equal to one and unmethylated cases equal to 33 and numbers of unmethylated cases in the non-cancer...

500 cases of Esophago-Gastroscopy were evaluated at the Shahid Moddares teaching and research medical center. Endoscopic diagnosis were:  38% Gastritis, 24% Duodenal Ulcer, 8% Esophageal Carcinoma, 6% Gastric Carcinoma, 6% Gastric Ulcer, 6% Hiatal Hernia, 3% Esophageal Varises.  In 68% of these cases Gastroscopy findings were in Agreement with Radiology reports. 

altered glycosylation of proteins in cancer cells is one of the main processes responsible for anaplasia, invasion and metastatic potential of neoplastic cells. lectins are nonimmunogenetic compounds which specifically detect certain terminal sugars of glycoconjugates. the aim of the present study was to identify the n-acetylgalactosamine (galnac) containing glycoconjugates in cancer cells in a...

background host genetic and environmental factors are involved in development of gastric cancer. tumor necrosis factor (tnf)-î±| has a key role in helicobacter pylori -induced gastritis. we analyzed the association between tnf-î± polymorphism and the risk of gastric cancer in an iranian population residing in northeastern iran. materials and methods in a case-control study, the genotyping was c...

Objective(s): Expression of HER2 in gastric carcinoma has direct prognostic and therapeutic implications in patient management. The aim of this study is to determine whether a relationship exists between standardized uptake value (SUV) and expression of HER2 in advanced gastric carcinoma. Methods: We analyzed the 18F-FDG PET/CT results of 109 patients that underwent gastrectomy for advanced gas...

background: to asses the status of two representative genes of cag pai i.e caga and cage of helicobacter pylori strains infecting iranian patients suffered from various clinical outcomes using one-step pcr. methods: a total of 120 h. pylori infected patients including non-ulcer dyspepsia, nud (n=81), peptic ulcer disease, pud (n=17), and gastric carcinoma, gc (n= 22) referred for endoscopy or g...