Background: Coronary artery diseases (CAD) is the most common cause of death in the developing counteries.  Atherosclerosis is the leading cause of CAD. A number of studies have shown that total leukocyte count is a risk factor for CAD but there is little information on the role of eosinophilia and allergy.  The aim of this study was to determine the relationship between eosinophilia and histor...

OBJECTIVES Gemifloxacin is a broad spectrum antibiotic and has shown excellent coverage against a wide variety of microorganisms. In this study, an attempt was made to evaluate the immunomodulatory potential of gemifloxacin in male swiss albino mice in vivo. MATERIALS AND METHODS Three doses of gemifloxacin 25 mg/kg, 50 mg/kg and 75 mg/kg were used intraperitoneally (IP) for the evaluation of...

In the present study, toxicity was developed by oral administration of AFB1 at a dose of (2μg/kg body weight) for 45 days in male mice. Curcuma longa (100 and 200 mg/kg body weight) and Curcumin (50 and 100 mg/kg body weight) were given individually and in combination with AFB1 for 45 days. At the end of 45 days, the blood samples were collected from various groups by heart puncture in eppendro...

This study investigated the immunotoxic potentials of raw and simulated leachates from Olushosun municipal solid waste landfill in rat using quantitative leucocyte and differential counts. Blood samples of rats intraperitoneally exposed to 1 – 25 % concentrations of each of the leachate samples for 48 hours were examined post treatment for leukocyte and differential counts. Compared to the nega...

We have studied the acute and subchronic oral toxicities of Calendula officinalis extract in male and female Wistar rats. A single acute C. officinalis extract dose of 2000 mg/kg dissolved in distilled water was administered by oral gavage for acute toxicity. Subchronic doses of 50, 250 and 1000 mg/kg/day were administered in drinking water. The major toxicological endpoints examined included a...

Anticoagulants and storage time’s effect on hemogram and differential leukocyte count in 26 Mugil cephalus was investigated. After blood collection, samples were put, in three microtubes containing respectively: ethylenediamine tetraacetic acid (EDTA), heparin, sodium citrate. Analysis were assessed immediately (T0) and 24 h (refrigerated at +4°C) after collection (T24). Statistical analysis sh...

The results of laboratory tests have little practical utility unless clinical studies have ascribed various states of health and disease to intervals of values. Several factors affect hematologic values, including race, environment, time of sampling, test method, blood collection site, gestational age and maternal factors. Since these factors vary in various populations, they can cause differen...

AIMS This study aims to investigate the influence of physical training on the immune system of diabetic rats. MATERIALS AND METHODS Adult male Wistar rats were distributed into Sedentary Control (SC), Trained Control (TC), Sedentary Diabetic (SD) and Trained Diabetic (TD) groups were used. Diabetes was induced by alloxan (32 mg/bw-i.v.). Training protocol consisted of swimming, at 32 +/- 1 de...

Reference values for the differential leukocyte count using an automated cytochemical method (Hemalog D) were determined in 1216 healthy children aged 0-16 years. Log-normal distributions for the absolute counts of all the separate cell types and for the total leukocyte counts were determined. For the relative values, a log-normal distribution for the eosinophils and basophils was also establis...

OBJECTIVE This study was aimed to investigate the prevalence rate and clinical characteristics of high altitude deterioration (HADT), which would provide a scientific basis for the diagnosis and prevention of HADT. SUBJECTS AND METHODS A total of 175 subjects, who had migrated to a high altitude (4516 m) for more than 1 year, were investigated. A questionnaire survey based on the symptoms of ...