Detection of Histoplasma capsulatum urinary antigen (UAg) is important for the initial diagnosis of infection and for monitoring of patient responses to antifungal therapy. This study evaluated an analyte-specific reagent (ASR) enzyme immunoassay (EIA) for the detection of H. capsulatum UAg from Immuno Mycologics, Inc. (IMMY) (Norman, OK) in comparison with routine testing with the MiraVista (M...

Histoplasma capsulatum is an intracellular fungal pathogen that causes respiratory and systemic disease by proliferating within phagocytic cells. The binding of H. capsulatum to phagocytes may be mediated by the pathogen's cell wall carbohydrates, glucans, which consist of glucose homo and hetero-polymers and whose glycosydic linkage types differ between the yeast and mycelial phases. The alpha...

65 year-old-male presented with a one-week history of high grade fever, fatigue and confusion which began abruptly two days after a cystoscopy procedure. Past medical history included pulmonary sarcoidosis diagnosed by mediastinal lymph biopsy, diabetes and hypertension. On admission he was febrile and confused with stable vital signs. Initial workup included negative Head CT and lumbar punctur...

Classical histoplasmosis is a cosmopolitan fungal infection caused by Histoplasma capsulatum variety capsulatum.1 H. capsulatum is a dimorphic fungus found in nature in its filamentous form, consisting of branched hyphae, which produce tuberculate macroconidia, the infective form of the fungus. When cultivated at 37 ◦C and in the tissues of infected people, it presents as budding yeast cells.1 ...

Histoplasmosis is caused by the dimorphic fungus - Histoplasma capsulatum. The presentation of histoplasmosis often disseminated, though primary intestinal involvement can rarely be seen in patients with cell mediated immune dysfunction like AIDS. We report a case renal allograft recipient, who had history COVID 19 infection and also underwent anti-rejection treatment for graft dysfunction, pre...

Reid, Scherer, Herbut, and Irving (I 942) noted nodules surrounded by haemorrhage in both maculae of a patient dying of systemic histoplasmosis. A relationship between a form of uveitis with specific morphological features and evidence of exposure to Histoplasma capsulatum was also suggested by Day (I 949), Krause and Hopkins (I 95 I), and Schlaegel (I 958). Woods and Wahlen (i959) described a ...