treatment, biologically. Levobunolol HCl occuserts were prepared using hydroxypropyl methylcellulose (HPMC, 3% & 4%), poly vinyl pyrrolidone (PVP, 1%), methyl cellulose (MC, 1% & 2%) as polymers by solvent casting technique with objectives of increasing contact time, achieving controlled release, reduction in frequency of administration and greater therapeutic efficacy. Based on their physioche...

The aim of the present study was the development of thermo-sensitive in-situ gels for in-vitro evaluation of ophthalmic delivery systems of ketorolac tromethamine (KT), based on methylcellulose (MC) in combination with hydroxypropylmethyl cellulose (HPMC). The gel temperature of 1% MC solution was observed at 60°C. It was found that 6% oral rehydration salt without dextrose (ORS) was capable to...

The use of uncoated fused silica capillary columns and hydroxypropylmethyl cellulose (HPMC) in capillary electrophoresis (CE) to separate DNA ladders and plasmids is described. In these studies HPMC is used as a sieving matrix to separate DNA. Many previous studies have focused on using coated and gel-filled capillaries to *Correspondence: F. A. Gomez, Department of Chemistry and Biochemistry, ...

An attempt was made to formulate Buccal patches of Isoxsuprine hydrochloride, a potent and long acting vasodilator and uterine suppressant , by using Hydroxyl propyl methyl cellulose(HPMC), Polyvinyl pyrolidone K-30 (PVP K-30) and Hydroxyl ethyl cellulose (HEC). Twelve batches of buccal patches were prepared by solvent casting technique in which the best formulation was found out. The polymers ...

This research aimed to investigate effects of dough improvers (trehalose; TR, sucrose ester; SE and hydroxylpropylmethylcellulose; HPMC) on microstructural, textural, rheological and baking properties of frozen dough with virgin coconut oil using central composite design (CCD). Frozen dough containing dough improvers had higher values of all properties compared to frozen dough without dough imp...

A colon-specific capsule with alginate beads containing a self-microemulsifying drug delivery system (SMEDDS) was developed and evaluated. The SMEDDS technique was used to improve the solubility of curcumin (Cur). After encapsulating the Cur-loaded SMEDDS, the alginate beads were placed inside an impermeable capsule body. A konjac glucomannan/lactose/hydroxypropyl methylcellulose (KG/Lac/ HPMC)...

The purpose of this investigation was to prepare a gastro retentive drug delivery system of famotidine tablets. Floating tablets of famotidine were prepared employing lipid solid dispersion spray drying technique with gelucire 50/13 and compritol 888 along with HPMC K100M, lactose, sodium bicarbonate and citric acid. The floating tablets were evaluated for uniformity of weight, hardness, friabi...