The objective of the present study was to develop a practical method to prepare a stable dispersion of TiO2 nanoparticles for biological studies. To address this matter a variety of different approaches for suspension of nanoparticles were conducted. TiO2 (rutile/anatase) dispersions were prepared in distilled water following by treated with different ultrasound energies and various dispersion ...

The aim of the present study was to prepare and evaluate an osmotically controlled mucoadhesive cup-core (OCMC) containing aceclofenac. A special technique was used while preparing an OCMC. Stability of OCMC was determined in natural human saliva, and it was found that both pH and device are stable in human saliva. OCMC was evaluated by weight uniformity, thickness, hardness, friability, swelli...

Cefdinir (Cef) is a third-generation cephalosporin antibacterial agent with an extended spectrum and low solubility permeability. In this study, cefdinir was prepared as nanosuspension lyophilized to powder. The further processed develop bilayer tablet. By utilizing the approach, first therapeutic action impacted by immediate part's rapid disintegration prolonged release from floating part achi...

Objective: The objective of this investigation was to formulate and evaluate effervescent pellets febuxostat achieve sustain release effect.
 Place Duration Study: APMC College Pharmaceutical education research, Department Pharmaceutics, Himatnagar-383001, between June 2019 July 2021.
 Materials Methods: gastro retentive were formulated using Sodium CMC HPMC K4M HPMCK15M as a polymer....

Objective: Butorphanol is a commonly used medication for the management of postoperative pain and suffers low bioavailability high first-pass metabolism. The objective current studies was to develop butorphanol tartrate-loaded dissolving microneedle patch overcome limitation metabolism without causing any discomfort patient. Methods: prepared using Lapox resin micro-molds. optimized box-Behnken...

Mucoadhesive buccal tablets containing ondansetron hydrochloride (ODH) were prepared using polymers like gelatin, chitosan, xanthan gum in varying concentration of 5, 10, 15% w/w and HPMC K4M 40% w/w by direct compression technique. Precompressional studies revealed good micromeritic properties of powder blend for compression and were found as per literature limits. The prepared tablets were ev...

Celecoxib is used in the treatment of osteoarthritis, rheumatoid arthritis, acute pain, joint inflammation and sport injuries. Long term administration of the drug results in such complications as gastrointestinaland renal disturbances and cardio-vascular complications. The main objective of the present study was to investigate the feasibility of delivering celecoxib incorporated in gel formula...

Background: More than 85% of young people around the world suffer from acne vulgaris, which is most prevalent chronic inflammatory skin illness. The study’s objective was to develop a herbal patch formulation contained quercetin, curcuminoids, and berberine HCl for treatment that utilizing ethyl cellulose HPMC K4M as polymers propylene glycol plasticizer. Materials Methods: Drug excipient compa...

The present investigation was undertaken with an objective of formulating modified release (MR) matrix tablets of Oxcarbazepine (OXC) an anti-epileptic drug, based on cellulose ether polymers like Hydroxy Propyl Methyl Cellulose (HPMC K4M and LVCR 100) and Hydroxy Propyl Cellulose (HPC JF) as drug release retardants to overcome poor patient compliance and exposure to high doses associated with ...