Background: Pulmonary tuberculosis (PT) is one of the endemic diseases in Iraq, and among the suggested predisposing factors are alleles of the human leukocyte antigen (HLA) system. We sought to investigate the association between HLA-class I (A and B) and -class II (DR and DQ) alleles in a sample of PT Iraqi patients.Methods: lymphocytes of 105 PT patients and 40 controls were phenotyped for H...

Severe cutaneous adverse drug reaction (SCAR) is considered to be a multifactorial drug side effect. This study was designed to investigate the epidemiology and human leukocyte antigen (HLA)-A and -B gene polymorphisms in pediatric patients with SCAR admitted in tertiary referral center, southwestern of Iran from 2013 to 2017. Demographic data, past allergy and autoimmune history, clinical pres...

Background: Human Leukocyte Antigen (HLA) is highly polymorphic and it commonly used as a marker for core population genital aspects such human migration, predisposition to diseases in tissue transplantation compatibility. Methodology: For our study authors have taken up sample size of 86 meta- analysis high-resolution frequency data the HLA allele. North Indian patients from tertiary centre we...

Allograft rejection is a significant cause of renal transplant failure which needs prompt diagnosis and treatment for graft salvage. Angiotensin II type 1 receptor antibody-mediated (AT1R-AMR) increasingly being identified as the etiology in kidney recipients with allograft but without detectable human leukocyte antigen (HLA) antibodies. While some reports have suggested that AT1R-AMR may be re...

2Fertility Clinic, Vilnius, Lithuania Human leukocyte antigen G (HLA-G) is a non-classical HLA class I molecule which can be expressed in the membrane-bound or soluble form and is well known for its tolerogenic properties. Increasing interest is now being addressed to the soluble forms, because they might have prognostic properties in the implantation and pregnancy process. The aim of our study...

Background: The human leukocyte antigen (HLA) matching between organ donor and recipient is an acceptable strategy in clinical transplantation since 1964. However, in bone marrow transplantation, finding matched donors is often problematic. Thus new method for down regulation of HLA can be an alternative strategy to solve this problem. Objective: To examine the effect of serum starvation on HLA...

OBJECTIVE To determine the association between mediastinal fibrosis and human leukocyte antigen (HLA) genes. DESIGN Case-control study. SETTING Vanderbilt University Medical Center. SUBJECTS Nineteen consecutive patients with mediastinal fibrosis who presented to the pulmonary clinic at Vanderbilt University Medical Center from 1987 to 1996. The control subjects were 21,086 whites who wer...

background: the human leukocyte antigen-drb1 (hla-drb1) locus is one of the most polymorphic human loci and has a crucial role in the immune system. assessing the allelic frequencies of hla-drb1 locus would be a fundamental factor in defining the origin of populations, relationships with other populations, disease association studies and the constitution of unrelated bone marrow donor registrie...