Human serum albumin (HSA) is an intrinsic protein and important carrier that transports endogenous as well as exogenous substances across cell membranes. Herein, we have designed and prepared resveratrol (RV)-loaded HSA nanoparticles conjugating RGD (arginine-glycine-aspartate) via a polyethylene glycol (PEG) "bridge" (HRP-RGD NPs) for highly effective targeted pancreatic tumor therapy. HRP-RGD...

As a well-known toxic pollutant, sulfide is harmful to human health. In this study, a simple and sensitive amperometric inhibitive biosensor was developed for the determination of sulfide in the environment. By immobilizing nanoporous gold (NPG) on glassy carbon electrode (GCE), and encapsulating horseradish peroxidase (HRP) onto NPG, a HRP/NPG/GCE bioelectrode for sulfide detection was success...

Background The implications of decentralisation on human resource for health management has not received adequate research attention despite the presupposition that the concept of decentralisation leads to the transfer of management authority and discretion for human resource management from national levels to subnational levels. This study aims at investigating the extent to which decent...

The detection of severe malaria in resource-constrained settings is often difficult because of requirements for laboratory infrastructure and/or clinical expertise. The aim of this study, therefore, was to explore the utility of a multiple antigen (HRP-2/pLDH) rapid diagnostic test (RDT) as a low-cost, surrogate marker of patients at high risk for complications of severe malaria. We reviewed pr...

The proposed “Tracking Resource Allocation Cognitive Strategies” tool (TRACS) allows for post-hoc visualization of the cognitive steps exhibited by a human operator while interacting with a multivariate resource allocation decision-support interface. This tool was applied to both mission planning for multi-criteria resource allocation for military strikes, and also multi-variable geospatial pat...

background: in this study, we evaluated the protective effects of water hyacinth root powder (hrp) on arsenic-mediated toxic effects in mice. methods: swiss albino mice, used in this study, were divided into four different groups (for each group n=5). the control group was supplied with normal feed and water, arsenic group (as-group) was supplied with normal feed plus arsenic (sodium arsenite)-...