Abstract There are several vaccines developed against COVID-19 infection. Inactivated viral usually well tolerated. We aimed to present a relapsing immune thrombocytopenia case following inactive vaccine. Here we report of inactivated vaccine in 60-year-old woman with history thrombocytopenia. The patient responded dexamethasone treatment and was discharged from the hospital full recovery. sugg...

  An inactivated agalactia vaccine was prepared with Mycoplasma agalactiae in fermenter. The culture was inactivated and subsequently adjuvanted with aluminum hydroxide gel. Four sheep and four goats were immunized with the experimental vaccine. Two doses of 1ml of vaccine were administered three weeks interval. Monthly, blood samples were taken from the vaccinated animals up to the fifth month...

Brum M.C.S., Caron L., Chowdhury S.I., Weiblen R. & Flores E.F. 2010. Immunogenicity of an inactivated bovine herpesvirus type 5 strain defective in thymidine kinase and glycoprotein E. Pesquisa Veterinária Brasileira 30(1):57-62. Setor de Virologia, Departamento de Medicina Veterinária Preventiva, Centro de Ciências Rurais, Universidade Federal de Santa Maria, Av. Roraima 1000, Camobi, Santa M...

The objective of this study was to determine the influence nonionic surfactants on effectiveness preservatives used in emulsions containing high surfactant content. Mixtures different concentrations were prepared between polyethoxylated (40) hydrogenated castor oil (PHCO) and polyoxyethylene sorbitan monooleate (PSO), with methylparaben, phenoxyethanol, ethylparaben, propylparaben, isobutylpara...

In this study, reverse genetics was applied to produce vaccine candidate strains against highly pathogenic avian influenza viruses (HPAIVs) of the H5N1 subtype. The H5 subtype vaccine strains were generated by a reverse genetics method in a biosafety level 2 facility. The strain contained the HA gene from the H5N1 subtype HPAIV attenuated by genetic modification at the cleavage site, the NA gen...

The protective efficacy of a subunit avian influenza virus H5 vaccine based on recombinant baculovirus expressed H5 haemagglutinin antigen and an inactivated H5N2 avian influenza vaccine combined with a marker antigen (tetanus toxoid) was compared with commercially available inactivated H5N2 avian influenza vaccine in young ducks. Antibody responses, morbidity, mortality, and virus shedding wer...

Aim The objective of the present study was to prepare a trivalent inactivated vaccine of Newcastle disease virus (NDV), H5N1, and H9N2 viruses. Materials and Methods Three monovalent and a trivalent vaccines were prepared by emulsifying inactivated NDV (LaSota strain), reassortant H5N1, and H9N2 viruses with Montanide ISA 71 oil adjuvant. Parameters used for evaluation of the efficacy of the ...

This paper describes the development of an in vitro assay to replace in vivo potency testing for the batch release of inactivated Newcastle Disease virus vaccines. The assay involves the extraction of inactivated antigen from oil emulsion vaccines, the most common adjuvant for poultry vaccines. An enzyme-linked immunosorbent assay (ELISA) is used to quantify the hemagglutininneuraminidase (HN) ...