نتایج جستجو برای: induced cholestasis
تعداد نتایج: 985254 فیلتر نتایج به سال:
Mitochondrial impairment is hypothesized to contribute to the pathogenesis of chronic cholestatic liver diseases. Mitofusin 2 (Mfn2) regulates mitochondrial morphology and signaling and is involved in the development of numerous mitochondrial-related diseases; however, a functional role for Mfn2 in chronic liver cholestasis which is characterized by increased levels of toxic bile acids remain u...
Hepatic cholestasis is characterized by elevated alkaline phosphatase and gama - glutamyl transpeptidase levels which is then followed by conjugated hyperbilirubinemia. It is classified into intrahepatic and extrahepatic cholestasis. Intrahepatic cholestasis indicates hepatocellular dysfunction or the presence of an obstructive lesion in intrahepatic bile ducts distal to biliary canalicular sy...
background: nitric oxide (no), a major chemical form of endothelium-derived relaxing factor and an important regulator of vascular tone, is released by endothelial cells. the role of no is not restricted to the vascular system, and it participates in the regulation of renal hemodynamics and renal excretory function. there are increasing evidences indicating that the elevated levels of no play a...
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