نتایج جستجو برای: inflammatory activity

تعداد نتایج: 1352118  

Background and purpose: Hyperglycemia contributes to type 2 diabetes and diabetes vascular complications by reduction of the activity of glyoxalase-I (GLO-I) and elevation of glycation, oxidative stress, and inflammatory markers. Linalool is reported to have beneficial effects on glucose metabolism in animal models of diabetes, so, this study aimed at investigating the effect of linalool on the...

Fateme Sadat Dashti, Hossein Hadinedoushan, Maryam Asadi,

Background and Aims: Plants as medicines have always played a vital role in human life. Tumor necrosis factor alpha (TNF)-α is one of the macrophage-derived inflammatory cytokine with pleotropic effects in the inflammation process. Some studies have been demonstrated that some of the Echinops species have anti-inflammatory activity. In fact, Echinops lasilepis is introduced as one of the ...

Hydrocotyle umbellata L. (Family Araliaceae) populary known as Acaricoba, is indicated in folk medicine for treatment of several inflammatory disorders. The goal of the present study is to evaluate the anti-inflammatory activity of the defatted ethanolic extract (DEE) of the aerial parts using carrageenan-induced rat paw oedema method. The levels of the pro-inflammatory cytokine interl...

Leptadenia reticulata was reported to be used for several medicinal purposes. The present study was undertaken to evaluate anti-inflammatory, analgesic and lipid peroxidation inhibition activities of L. reticulata. The anti-inflammatory assay was performed by λ-carrageenan and formalin induced paw edema test. Pro inflammatory mediators (IL2, IL6, TNF-α) in serum of treated and control organism ...

Achinto Saha, AKM Matior Rahman, Mesbahuddin Ahmad, Ranajit Kumar Sutradhar, Samar Kumar Guha, Sitesh Chandra Bachar,

In the present study, the analgesic and anti-inflammatory activities of a new alkaloid (5′-Hydroxymethyl-1′-(1,2,3,9-tetrahydro-pyrrolo [2,1-b] quinazolin-1-yl)-heptan-1-one) (compound 1), isolated from Sida cordifolia Linn. was investigated in animal models. The analgesic activity was investigated in the acetic acid induced writhing and the radiant heat tail flick model in mice a...

M Mojeeb R Zafar S Ahmad S Asmari

To determine the pharmacological (Anti-inflammatory) potential of in-vitro cultures of Asparagus racemosus. Anti-inflammatory activity of methanolic extracts of shoot, root their calli and genetically transformed shoot culture was performed using carrageenan induced rat paw edema method. The albino rats were treated orally with two dosage (500 or 1000 mg/kg body weight of rats) of drugs, one ho...

A. Maajitha Begam C. Christobher K. Peer Mohamed, P KandasamyPrabakar

Abstract Nature has been a wellspring of therapeutic operators for a huge number of years and an exceptional number of present day drugs have been secluded from common sources. Higher plants, as wellsprings of restorative mixes, have kept on assuming a prevailing part in the support of human wellbeing since old circumstances. More than half of all cutting edge clinical medications are of...

اسماعیلیان, مجید, خدادادی, علی, عاقل, نسرین,

N Aghel , PhD A Khodadadi , PhD M Asmaeiliyan , PhD Received: 23 April, 2007 Accepted: 27 Nov, 2007 ABSTRACT Background & Aims: Metalloproteinase matrix (MMPs), a family of zinc and calcium dependent enzymes, is produced by a wide range of stromal and inflammatory cells. MMPs are capable of degrading all of the compounds of extra cellular matrix. The role of metalloproteinase matrix in pat...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه پیام نور - دانشگاه پیام نور استان تهران - دانشکده علوم پایه 1389

چکیده : مقدمه : ابتلا به آترواسکلروز در بیماران دیابتی بیشتر از افراد سالم می باشد . هموسیستئین می تواند به عنوان یکی از عوامل خطرزای آترواسکلروز مطرح با شد . آنزیم لستین کلسترول آسیل ترنسفراز نقش مهمی را در پاک سازی کلسترول آزاد در بافت ها از طریق عملکرد hdl-c بر عهده دارد .هدف از این مطالعه تعیین سطح فعالیت لستین کلسترول آسیل ترنسفراز (lcat activity ) در بیماران دیابتی نوع 2 در مقایسه با افر...

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