multiple sclerosis (ms) is an autoimmune inflammatory, demyelinating disease of human central nervous system. experimental autoimmune encephalomyelitis (eae) is the commonly used animal model of ms. calorie restriction has been found to reduce inflammation and autoimmune responses and promote neuroprotection. in this study we evaluated the effects of intermittent feeding protocol of the calorie...

Introduction: Ewing’s sarcoma localized to foot is extremely rare. Local control is mandatory because of the aggressive nature of the tumor. Therapeutic options for these local tumors include neoadjuvant chemotherapy followed by surgery. Case Presentation: A 16-year-old male patient presented with 8-month history of progressive swelling and intermittent pain of the right great toe. Plain radiog...

INTRODUCTION Refractory pleural effusion in systemic immunoglobulin light chain amyloidosis without cardiac decompensation is rarely reported and has a poor prognosis in general (a median survival of 1.6 months). Moreover, the optimum treatment for this condition is still undecided. This is the first report on the successful use of vincristine, adriamycin and dexamethasone chemotherapy for refr...

In the everyday routine practice of a medical oncologist, it is not so infrequent that a patient with prosthetic heart valve who is on warfarine therapy has to receive chemotherapy, . This is a problematic situation for a medical oncologist since, drug interactions of warfarine with various chemotherapeutics are unpredictable, the result may either be thrombosis or bleeding. Furthermore, chemot...

Leiomyosarcomas arising from the wall of blood vessels are rare and aggressive neoplasm. We report a case of a previously healthy 66-year-old woman who presented with intermittent abdominal pain, progressive constipation, and weight loss. Abdominal computed tomography showed a 12 cm solid heterogeneous tumor in the tail of the pancreas. The patient subsequently underwent surgical resection of t...

objective to evaluate the efficacy and common side effects of intermittent clonazepam in febrile  seizures. materials & methods this study was an experimental trial designed to determine the efficacy of intermittent clonazepam in febrile seizures .thirty patients with an age range of 6 months to 5 years (60% male, 40% female) were studied. children with a history of psychomotor delay, abnormal ...

results compared to pre-op scores, pf, ss, and vas scores for back, buttock and leg pain had a significant mean decrease at 6, 12, 24 months post-op (p < 0.05). based on the zcq and vas scores, a success rate of 79% (27.34), 78% (30.38) and 74% (17.23) were achieved at six months, 12 months, and 24 months respectively. conclusions x-stop is a safe and effective treatment for nic that provides m...

OBJECTIVE To report a case of rectal cancer in a patient with Peutz-Jeghers syndrome (PJS). CLINICAL PRESENTATION AND INTERVENTION A 20-year-old woman with intermittent bloody stool of 4 months was admitted for examination. Gastroendoscopy revealed multiple polyps involving the stomach, small intestine, colon and a rectal adenocarcinoma. A diagnosis of PJS was made based on intestinal polyps ...

A 26-year-old man, diagnosed with acute myelogenous leukemia had multiple inflammatory pseudotumors (IPT) in the liver. The patient presented complete remission after remission induction therapy, and then showed right upper quadrant discomfort and intermittent fever. An ultrasonography disclosed multiple hypoechoic nodules in the liver. A biopsy of the nodules showed focal liver cell necrosis w...

This is the case of a 7-year-old girl with a history of migraine headaches who presented with a head tilt to the left and worsening headaches. Papilloedema was found on ophthlamoscopy. She had an intermittent history of migraine-type headaches for the past year. Oral naproxen 375mg twice daily provided some relief of the headaches initially but they slowly worsened and head tilt appeared. A med...