OBJECTIVES/HYPOTHESIS To determine the prevalence of elevated intracranial hypertension in patients with spontaneous cerebrospinal fluid otorrhea (SCSFO). STUDY DESIGN Case series with chart review at a tertiary care academic medical center following institutional review board approval. METHODS A retrospective review was performed of patients undergoing operative repair of SCSFO between Jan...

Traumatic brain injury and stroke are both characterized by an ischemic core surrounded by a penumbra of low to hyperemic flows. The underperfused ischemic core is the focus of edema development, but the source of the edema fluid is not known. We hypothesized that flow of edema fluid into the tissue is derived from cerebral venous circulation pressure, which always exceeds intracranial pressure...

High dose barbiturates were used to treat intracranial hypertension in 15 patients with nontraumatic brain lesions; (3 hypertensive hemorrhage, 4 subarachnoid hemorrhage, 5 infarction, 2 global anoxia-ischemia and 2 encephalitis). All had persistently raised intracranial pressure (ICP) while being treated with aggressive conventional therapy. The addition of barbiturates caused an initial lower...

Intra-abdominal hypertension (IAH) is defined as intra-abdominal pressure (IAP) above 12 mmHg and may be categorized as Grade I (12-15 mmHg), Grade II (16-20 mmHg), Grade III (21-25 mmHg) or Grade IV (> 25 mmHg). Recurrent or persistent IAP above 20 mmHg, in association with failure of at least one organ, is called Abdominal Compartment Syndrome (ACS). The mortality and morbidity of IAH and ACS...

Ursino, M., C. A. Lodi, S. Rossi, and N. Stocchetti. Intracranial pressure dynamics in patients with acute brain damage. J. Appl. Physiol. 82(4): 1270–1282, 1997.—The time pattern of intracranial pressure (ICP) during pressurevolume index (PVI) tests was analyzed in 20 patients with severe acute brain damage by means of a simple mathematical model. In most cases, a satisfactory fitting between ...

Following recent studies, the automatic analysis of intracranial pressure pulses (ICP) seems to be a promising tool for forecasting critical intracranial and cerebrovascular pathophysiological variations during the management of many neurological disorders. MOCAIP algorithm has recently been developed to automatically extract ICP morphological features. The algorithm is able to enhance the qual...

The effect of vecuronium on intracranial pressure (ICP) was investigated in six cats with normal and increased ICP. Cats were anaesthetized with pentobarbitone 33 mg kg-1 i.p. and acepromazine 0.6 mg kg-1 i.p., the trachea was intubated, and the lungs ventilated with nitrous oxide in oxygen. Mean arterial pressure (MAP), heart rate (HR), twitch response and ICP were recorded continuously. After...