Small doses of L2C leukemic cell suspensions inoculated intradermally into strain 2 and F1 hybrid guinea pigs induced leukemic tumors that regressed spontaneously in about 50% of animals, whereas s.c. inoculation induced uniformly generalized leukemia. Because of the behavioral differences between the s.c. and intradermal tumors, it appeared of interest to examine their comparative morphology b...

Although various injection techniques of hyaluronic acid (HA) filler for facial rejuvenation have been developed, correction of deep wrinkles/grooves, such as the nasolabial fold (NLF), with intradermal or subdermal injections remains difficult. We tested the intradermal HA injection method to place multiple HA struts by (1) inserting a small needle perpendicularly to the wrinkle and (2) inject...

Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transderma...

Microneedle-mediated Transdermal and Intradermal Drug Delivery covers the major aspects relating to the use of microneedle arrays in enhancing drug delivery applications. It provides an overview of the various methods employed to design and produce microneedles, from the different materials involved to the importance of application methods. It carefully and critically reviews ongoing transderma...

When purified human C'1 esterase is injected intradermally in man, increased vascular permeability results. This effect is not blocked by soybean trypsin inhibitor and is not abolished by pretreatment with the antihistamine, pyribenzamine, or by compound 48/80. Thus, the effect is not due to the release of endogenous histamine. The decreased permeability response of individuals with a specific ...

The external auditory canal is an uncommon location for the nevi that are common benign tumors of the skin. A papillomatous lesion was detected in the external auditory canal of the patient who was on follow-up for acute otitis externa. The lesion which resembled a nevus was excised and was diagnosed as an intradermal nevus in pathological examination. The clinical and pathological picture of t...