background: hepatitis b virus is one of the most common causes of chronic liver diseases. vaccination is the best way of prophylaxis and is of utmost importance. this study was conducted to compare the prophylactic effect of intradermal and intramuscular injection of hepatitis b vaccine. methods: a blind randomized clinical trial was performed among subjects who presented to the infectious dise...

There has been a recent resurgence of interest in intradermal vaccine delivery. The physiological advantages of intradermal vaccine delivery have been known for some time, but the difficulties associated with performing an intradermal injection have historically limited its use. New delivery systems currently in development facilitate convenient intradermal vaccination, unlocking the potential ...

OBJECTIVES A comparative study of intradermal smear in the diagnosis of malaria in symptomatic pregnant women. Venous blood served as the control. PATIENTS AND METHODS Fifty consecutive symptomatic pregnant women were recruited. Thick films of both venous and intradermal blood were examined. Questionnaires were used to determine patients' preference for the two techniques. Tests of statistica...

Antibodies are required to control blood-stage forms of African trypanosomes in humans and animals. Here, we report that intradermal infections by low numbers of African trypanosomes are controlled by innate resistance but prime the adaptive immune response to increase susceptibility to a subsequent challenge. Mice were found 100 times more resistant to intradermal infections by Trypanosoma con...

PURPOSE To prepare for vaccine shortages under an influenza pandemic, several antigen-sparing strategies have been investigated. This study was aimed to evaluate the immunogenicity of influenza vaccine at reduced intradermal and full intramuscular dose. MATERIALS AND METHODS We compared the effect of one-fifth and one-half intradermal doses to the full intramuscular dose on immunogenicity in ...

BACKGROUND Although there are some published data about the prevalence of honeybee and vespid venom allergy from Turkey, there has been no report about Hymenoptera venom immunotherapy practice. Our aim was to determine the characteristics of Hymenoptera venom hypersensitivity and venom immunotherapy practice in Ankara, Turkey. METHODS Demographic and clinical data, intradermal test, and serum...

progesterone hypersensitivity (ph) is a rare clinical condition that  displays hypersensitivity to  endogenous  or  exogenous progesterone.  it  is characterized by cyclic dermatologic manifestations at the end of the luteal phase that disappear some days after menses. we present  a  case of  24-year-old woman  showing severe angioedema attacks occurring from the first day of her menstruation a...