Focused Ion beam (FIB) based tools have become the preferred method to prepare TEM lamellas, largely due to their high resolution imaging capabilities used to identify the site of interest. The quality and thickness of samples has become paramount in order to take full advantage of the ever increasing resolution in aberration corrected TEMs and accurately controlling the lamella thickness at th...

Malignant mesothelioma (MM) is extremely aggressive and a typical refractory cancer. In this study we investigated how effective on killing MM cells by carbon ion beam alone or in combination with cisplatin (CDDP) in vitro. Carbon ion beam (at the center of SOBP with 50 keV/µm of average LET) dose-independently suppressed MM cells MESO-1 and H226 cell viability and in combination with CDDP (25 ...

Patterning with a focused ion beam (FIB) is an extremely versatile fabrication process that can be used to create microscale and nanoscale designs on the surface of practically any solid sample material. Based on the type of ion-sample interaction utilized, FIBbasedmanufacturing can be both subtractive and additive, even in the same processing step. Indeed, the capability of easily creating thr...

ITEP in collaboration with MEPHI and HCEI (Tomsk) develops the high intensity ion beam generation and transport systems for low energy (1 – 50 keV) ion implantation. Such facilities are used for semiconductor technology. The Bernas type ion source is used for the ribbon ion beam production. The periodical system of electrostatic lenses (electrostatic undulator) was proposed for ribbon beam tran...

i Executive summary High power proton accelerators (HPPAs) are at the heart of many future large-scale scientific facilities such as a spallation-neutron source, Neutrino Factory and the Muon Collider, high energy physics at the energy or intensity frontier, accelerator driven sub-critical systems, and the transmutation of nuclear waste. Controlling beam-loss induced machine activation during i...

The ionization of residual gas by an electron beam in an accelerator generates ions that can resonantly couple to the beam through a wave propagating in the beam-ion system. Results of the study of a beam-ion instability [1,2] are presented for a multi-bunch train taking into account the decoherence of ion oscillations due to the ion frequency spread and spatial variation of the ion frequency. ...

A helium ion beam source (23 kV/2.0 A) has been constructed for studying fast-ion physics in the cylindrical magnetized plasma of the large plasma device (LAPD). An inductive RF source produces a 10(19) m(-3) density plasma in a ceramic dome. A multi-aperture, rectangular (8 cm × 8 cm) three-grid system extracts the ion beam from the RF plasma. The ion beam is injected at a variety of pitch ang...

introduction: this study was carried out to investigate calcific tissue formation against mineral trioxide aggregate (mta) after pulp capping. materials and methods: the pulps of six teeth from four dogs were exposed and capped with mta. after extraction each tooth was sectioned into halves. each half was then further sectioned in the mesiodistal or buccolingual direction. calcified tissue of t...

Beijing Radioactive Ion-beam Facilities Isotope Separator On-Line (BRISOL), aiming to generate short life radioactive ion beam (RIB) on-line, is being constructed at China Institute of Atomic Energy(CIAE). Up to now, construction of major equipment for BRISOL is completed, including ion source, vacuum system, separator, optical element, and beam diagnostic system, and assembling is underway in ...