نتایج جستجو برای: keywords toxoplasma gondii
تعداد نتایج: 1988236 فیلتر نتایج به سال:
Over the past few years, a number of new nucleic acid extraction methods and extraction platforms using chemistry combined with magnetic or silica particles have been developed, in combination with instruments to facilitate the extraction procedure. The objective of the present study was to investigate the suitability of these automated methods for the isolation of Toxoplasma gondii DNA from am...
Toxoplasma gondii, a cosmopolitan protozoan parasite, is known to induce behavioural alterations in rodents and may exert an effect on human personality and behaviour. The mechanism of parasite-induced alterations in host behaviour has not been described, but it was hypothesized that development of Toxoplasma tissue cysts in the brain could affect the dopaminergic neuromodulatory system. In thi...
Toxoplasma gondii is a ubiquitous protozoan parasite that is estimated to infect one-third of the world’s human population causing a wide range spectrum of diseases. Reports on the prevalence of T. gondii infection among infertile females are scarce. This case-control study aimed to screen the infertile females and pregnant controls for Toxoplasma infection investigating a possible association ...
The host cell penetration of Toxoplasma gondii was studied with reference to synthesis of a penetration-enhancing factor and the penetrative capacity of the parasites during the various phases of the infectious cycle. HeLa cells as suspension or monolayer cultures were infected with Toxoplasma. After a lag phase shorter than 1 hr, there was a synthesis of penetration-enhancing factor demonstrab...
Flourescent antibody test (FAT) was applied to determine the cross-reactivities of monoclonal (mAb), polyclonal (pAb) antibodies to Neospora, Toxoplasma and Cryptosporidium and antisera from cattle naturally infected with Neospora canium against antigens from a number of sources. Both mAb and pAb to Neospora reacted strongly (FAT titre up to 2560) with the homologous antigens and demonstrated w...
Toxoplasma gondii primary infection in pregnancy is associated with poor obstetric outcomes. This study aimed to determine the seroprevalence of Toxoplasma infection in pregnant migrant and refugee women from Myanmar attending antenatal care in Thailand. A random selection of 199 residual blood samples from first antenatal screen in 2014-2015 was tested for Toxoplasma IgG and IgM antibodies. Se...
Background and purpose: Toxoplasmosis is an infection caused by an intercellular protozoan called Toxoplasma gondii. Toxoplasma has global expansion and its prevalence is different in regions according to geographical conditions, habits and history of contact with cats. The present study determined the seroepidemiology of toxoplasma in pregnant women attending health centers in two cities i...
Background and purpose: Toxoplasma gondii is a protozoon with worldwide distribution. In spite of increasing information about its biology, treatment of toxoplasmosis is restricted to a few drugs and unfortunately using of each of drugs is associated with significant side effects in patients. It seems that investigation on alternative drugs is necessary. Materials and methods: In case group, c...
The precise diagnosis of the acute toxoplasmosis in pregnant women and immunocompromsied patients has critical importance. Most of the commercially available assays use the whole Toxoplasma soluble extract as the antigen. However, the assays currently available for the detection of specific anti-Toxoplasma antibodies may vary in their abilities to detect serum immunoglobulins, due to the lack o...
The inner membrane complex (IMC) of Toxoplasma gondii as a peripheral membrane system has unique and critical roles in parasite replication, motility and invasion. Disruption of IMC sub-compartment protein produces a severe defect in T. gondii endodyogeny, the form of internal cell budding. In this study, we generated T. gondii virus-like particle particles (VLPs) containing proteins derived fr...
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