Hepatobiliary scintigraphy is a sensitive method for intra & extera hepatic bile leak diagnosis. Bile lead may be seen after hepatobiliary surgery, trauma, inflammatory disease or malignant neoplasms. Although sonography and CT scanning are useful for diagnosis of peritoneal or perihepatic fluid, they cannot prove bile ascites. Hepatobiliary scintigraphy with Tc-99m-IDA agents is a physio...

Systemic Capillary Leak Syndrome (SCLS) is a rare disorder characterized by increased capillary hyperpermeability leading to hypovolemic shock due to a markedly increased shift of fluid and protein from the intravascular to the interstitial space. Hemoconcentration, hypoalbuminemia and a monoclonal gammopathy are characteristic laboratory findings. Here we present a patient who suffered from SC...

Spontaneous Intracranial Hypotension (SIH) was first described over 60 years ago by Schaltenbrand and termed “aliquorrhea”1. In 1997, this syndrome was defined by a classical triad of postural headaches, low cerebral spinal fluid (CSF) pressure and imaging abnormalities2. More recent evidence has redefined this concept and our understanding of the pathological mechanism, as well as the variable...

Introduction: Esophageal reconstruction is associated with significant blood loss and blood transfusion rates. Blood transfusion is a quick method of correction of anemia and rapid restoration of intravascular volume. However, concerns exist about the side effects of blood transfusion on the anastomotic complications. This prospective study aimed to report the impact of intraoperative blood tra...

OBJECTIVES There is intense interest in lung volume reduction surgery (LVRS) for treatment of severe symptomatic emphysema. LVRS results in objective and subjective improvement in lung function in selected patients. However, LVRS is complicated by substantial morbidity, including prolonged pulmonary air leak associated with resection of emphysematous lung tissue. In this study, we investigated ...

PURPOSE Isolated limb perfusion (ILP) with tumor necrosis factor (TNF), interferon gamma, and melphalan (M) has been reported to result in high response rates for extremity melanoma and sarcoma. We have evaluated the relationship of systemic TNF exposure to induction of several secondary mediators and incidence of systemic toxicity. PATIENTS AND METHODS Nineteen patients with extremity melano...

BACKGROUND In edentulous patients, it may be difficult to perform face mask ventilation because of inadequate seal with air leaks. Our aim was to ascertain whether the "lower lip" face mask placement, as a new face mask ventilation method, is more effective at reducing air leaks than the standard face mask placement. METHODS Forty-nine edentulous patients with inadequate seal and air leak dur...

BACKGROUND Although leak compensation has been widely introduced to acute care ventilators to improve patient-ventilator synchronization in the presence of system leaks, there are no data on these ventilators' ability to prevent triggering and cycling asynchrony. The goal of this study was to evaluate the ability of leak compensation in acute care ventilators during invasive and noninvasive ven...

hepatobiliary scintigraphy is a sensitive method for intra & extera hepatic bile leak diagnosis. bile lead may be seen after hepatobiliary surgery, trauma, inflammatory disease or malignant neoplasms. although sonography and ct scanning are useful for diagnosis of peritoneal or perihepatic fluid, they cannot prove bile ascites. hepatobiliary scintigraphy with tc-99m-ida agents is a physiolo...

Cardiac calsequestrin (Casq2) is thought to be the key sarcoplasmic reticulum (SR) Ca2+ storage protein essential for SR Ca2+ release in mammalian heart. Human CASQ2 mutations are associated with catecholaminergic ventricular tachycardia. However, homozygous mutation carriers presumably lacking functional Casq2 display surprisingly normal cardiac contractility. Here we show that Casq2-null mice...