The mechanism of the cAMP involvement in regulation of cellular functions was studied here using a novel functional assay (antigen receptor-triggered exocytosis of granules) of cloned cytotoxic T lymphocytes (CTL). We suggest that cAMP-dependent protein kinase, protein kinase A, counteracts the protein kinase C and Ca2+-mediated stimulatory T-cell antigen receptor (TcR)-triggered biochemical pa...

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Recent developments in computer and communication technologies have led to a new type of large-scale resource-constrained wireless embedded control systems. It is desirable in these systems to limit the sensor and control computation and/or communication to instances when the system needs attention. However, classical sampled-data control is based on performing sensing and actuation periodicall...

On 30th October 2020, the eastern Aegean Sea was shaken by a Mw = 7.0 earthquake. The epicenter located near northern coasts of Samos island. This tectonic event produced an uplift whole island as well several cases infrastructure damage, while small tsunami followed mainshock. Underwater and coastal geological, geomorphological, biological observations measurements were performed at entire coa...

Abstract The East Antarctic Ice Sheet stores a vast amount of freshwater, which makes it the single largest potential contributor to future sea-level rise. However, lack well-constrained geological records past ice sheet changes impedes model validation, hampers mass balance estimates, and inhibits examination loss mechanisms. Here we identify rapid ice-sheet thinning in coastal Dronning Maud L...