Sperm DNA fragmentation (sDF) represents a threat to male fertility, human reproduction and the health of the offspring. The causes of sDF are still unclear, even if apoptosis, oxidative assault and defects in chromatin maturation are hypothesized. Using multicolor flow cytometry and sperm sorting, we challenged the three hypothesized mechanisms by simultaneously evaluating sDF and signs of oxi...

Background Infertility and fertility decline are quite a conundrum for medicine, rampant among 10-15 percent of couples. In about 40 percent of cases, men are the main culprit. Since sperm production disorders are the focal cause of man infertility, insights into these disorders and taking action to ameliorate the situation is quite vital. The current study concentrates on infertility due to sp...

Background: The aim of present study was to estimate the levels of some minerals ( Zn, Se , Ca , Mg , Na and K ).Also relationships between mentioned components and some sperm parameters and the infertility period were studied as well. Materials and Methods: This study was performed on human semen specimens obtained from Asthenospermic patients (101 specimens) and Normospermic males (61 specime...

The objective of this study was to investigate whether medical therapy can reduce sperm aneuploidy levels and improve the results of intracytoplasmic sperm injection (ICSI) in patients with severe idiopathic oligoasthenoteratospermia (OAT). Thirty-three infertile couples requiring ICSI because of severe idiopathic OAT after at least one unsuccessful ICSI cycle were considered. Semen parameters ...

fresh semen obtained from infertile men occasionally exhibits the total absence of motile sperm (100%asthenozoospermia). vitality tests may reveal that a proportion of the immotile sperm has functional membranes, which are considered viable. an easy test for the prior determination of sperm viability may assist in sperm selection for the microinjection of oocytes. the main objective of this stu...

Quassia amara is a medicinal plant with several pharmacological properties. There are preliminary reports implicating this plant in male reproductive toxicology. Single daily oral administration of methanol extract of Quassia amara stem bark for 6 weeks resulted in a significant reduction in the weight of the testes, caudal epididymis and seminal vescicle. Caudal epididymal sperm parameters sho...

Reproductive and growth data were obtained on 779 and 564 yearling beef heifers and bulls, respectively, that had sires with yearling scrotal circumference data at the San Juan Basin Research Center, Hesperus, CO. Partial regression coefficients of reproductive and growth traits on inbreeding (FXC) and age of the individual and adjusted scrotal circumference of sire (SCSI) were obtained. Growth...

Internal fertilization requires live sperm to be transferred from male to female before egg fertilization. Both males and females assist the insemination process by providing sperm with glandular secretions, which have been inferred to contain subsets of proteins that maintain sperm viability. Here we show that in the honeybee (Apis mellifera) secretions of the male accessory glands, the major ...

Studies confirm that male sperm counts are declining, and environmental factors, such as pesticides, exogenous estrogens, and heavy metals may negatively impact spermatogenesis. A number of nutritional therapies have been shown to improve sperm counts and sperm motility, including carnitine, arginine, zinc, selenium, and vitamin B12. Numerous antioxidants have also proven beneficial in treating...

This study determined the effects of Trichomonas vaginalis trophozoites, subcellular fractions, and medium from axenic T. vaginalis cultures on human sperm motility and viability. Spent medium (pH 7.0) caused complete cessation of sperm motility after 15 minutes incubation. Trophozoite soluble fraction or formalin-killed trophozoites caused a 50 percent reduction in sperm motility, compared to ...