Squamous cell differentiation (SCD) may occur in papillary thyroid carcinoma (PTC) only at metastatic sites. We have studied cytokeratin CK5/6 and P63 along with TTF1 (thyroid transcription factor 1)  and B-Raf (V-Raf murine sarcoma viral oncogene homolog B1) immunohistochemical expression in neck lymph node metastases of thyroid PTC showing SCD. The patient (21-years) presented wit...

meningioma is usually a benign central nervous system (cns) tumor. metastasis is rare; however if it does occur the most metastatic sites are the liver and lungs. here, two cases of cns meningioma with metastasis to cervical lymph nodes are reported. the first case, a 48 year-old man developed cervical lymph node metastasis nine years after primary tumor diagnosis. the second case, a 23 year-ol...

introduction: there is a consensus in the literature that sentinel lymph node biopsy is the standard procedure for axillary staging in early stage (i and ii) breast cancer patients. usually during lymphoscintigraphy, the location of the sentinel lymph node is marked on the skin by an indelible ink. in this study we evaluated this issue in our patients. methods: 40 patients with the clinical dia...

background and objective: fine needle aspiration cytology (fnac) is a well-established method of diagnosis in palpable masses of various sites. this study was conducted to evaluate the usefulness of fnac as a diagnostic tool in the management of patients with cervical lymphadenopathy. patients and methods: totally 178 patients admitted to loghman-hakim hospital , tehran, iran, with cervical mas...

the charts of 27 patients with kawasaki disease (kd) admitted to nemazee hospital in shiraz from january 1991 to october 1998 were reviewed to identify the results of mean peroxidase index (mpxi) values, a measure of neutrophil staining intensity, obtained by the technicon hi analyzer (technicon instruments corp., tarrytown, ny) within the first 10 days of the illness 2 separate groups of patie...

background : interleukin (il)-4 is a member of t helper 2 (th2) axis produced by t-lymphocyte and mast cell. it has been shown that il-4 expression changes in tumor tissues. the main objective of this study is to investigate the expression of il-4 mrna in patients with laryngeal squamous cell carcinoma (lscc) with or without lymph node involvement. materials and methods: mrna expression of il-4...

SUMMARY Castleman's disease is a rare condition. In its classic form Castlema's is a solitary lesion, two third of patients have tumour like mass in the mediastinum. Extrathoracic sites also could be affected including those where lymph nodes normaly occur ancl rarely tissues where lymph nodes are not found. More recently there have been several reports of patients with multi centeric involvem...

introduction: kikuchi-fujimoto disease or histocytic necrotizing lymphadenitis is a rare, benign, self-limited condition characterized by constitutional symptoms, lymphadenopathy, and skin lesions and often affects young adult females.the etiology is unknown although viruses and autoimmune mechanisms has been suggested. diagnosis is fundamentally based on the affected lymph node biopsy.the pati...