Aim: To determine the frequency of non malignant hematological causes of pancytopenia. Bone marrow examination of 148 cases of suspected hematological disorders was carried out in a DHQ KDA Hospital, Kohat from Jan. 2011to Dec. 2013. Results: Among the non malignant hematological disorders, megaloblastic anemia was the most common disorder i.e., (18.2%) followed by aplastic anemia (8.8%), ITP (...

Deficiency of vitamin B12 and/or folic acid as a cause of pyrexia, though known, is rarely reported in literature. We aimed to report a case in a 51 year old woman, who presented with fever and pancytopenia and was diagnosed to have megaloblastic anemia secondary to vitamin B12 and folate deficiency. The pyrexia subsided following the intramuscular injection of vitamin B12 and oral folic acid a...

Serum pepsinogen levels have been compared in 40 patients with severe megaloblastic anaemia with those obtained from 62 normal subjects, and with levels in 20 patients with pernicious anaemia in remission, 46 patients with iron-deficiency anaemia, and 18 patients with a duodenal ulcer. The range in the normal subjects was 55 to 482 units per ml. It is suggested that a level of below 90 units pe...