OBJECTIVE To compare the 24-month course of health-related quality of life (HRQoL) in patients with long-standing RA treated with a conventional synthetic (cs) or a first, second or third biologic (b) DMARD in daily rheumatological care. METHODS Patients enrolled in the German biologics register RABBIT who were observed over at least 12 months were stratified according to the nth bDMARD start...

PURPOSE This study examined anxiety and depression among 108 North Korean adolescent and young adult (age, 12-29 years) defectors who settled in South Korea, and evaluated the relationship between their mental health and health-related quality of life (HRQoL). MATERIALS AND METHODS Subjects completed a questionnaire that included the Hospital Anxiety and Depression Scale (HADS), the Short For...

Conflict of interest: none. ABSTRACT Objective: To evaluate the diagnostic sensitivity, specificity, and agreement of the Dementia Rating Scale with clinical diagnosis of cognitive impairment and to compare its psychometric measures with those from Mini Mental State Examination. Methods: Eighty-six elders from a long-term care institution were invited to participate in a study, and fifty-eight ...

BACKGROUND The Lysholm knee scale, first published in 1982, is an eight-item questionnaire designed to evaluate patients after knee ligament injury. However, as a tool developed in English, its use as a validated instrument has been limited to English-language populations. QUESTIONS/PURPOSES The objectives of this study were to test the ease of use, reliability, and validity of a Turkish-lang...

INTRODUCTION Positive mental health is increasingly recognized as an important focus for public health policies and programs. In Canada, the Mental Health Continuum-Short Form (MHC-SF) was identified as a promising measure to include on population surveys to measure positive mental health. It proposes to measure a three-factor model of positive mental health including emotional, social and psyc...

the factors such as disease can disrupt homeostasis, resulting in perturbations of endogenous biochemicals that are involved in key metabolic profiles. metabonomics is useful technique to quantitative description of endogenous metabolites present in a biological sample such as urine, plasma and tissue. high resolution 1 h nuclear magnetic resonance (nmr)-based metabonomics is a technique used t...

There is a need to validate screening measures of affective and generalized anxiety disorders for use in epidemiological surveys of mental health in the general population. This study examined the diagnostic accuracy of the Patient Health Questionnaire (PHQ-9), Goldberg Anxiety and Depression Scales (GAS, GDS) and the 12-item Short Form Health Survey (SF-12) Mental Health Component Summary Scal...