The preparation of crystalline bis-trimethylsilylcefamandole (7) and its utility in the preparation and purification of cefamandole are described. Although stable to solvolysis in isopropyl alcohol, 7 underwent smooth conversion to cefamandole in the presence of water, methanol, or ethanol.

Computational studies of structural and catalytic properties single atom catalysts suggest they are attractive candidates for methane-to-methanol conversion.

Acetogens are efficient microbial catalysts for bioprocesses converting C1 compounds into organic products. Here, an adaptive laboratory evolution approach was implemented to adapt Sporomusa ovata for faster autotrophic metabolism and CO2 conversion to organic chemicals. S. ovata was first adapted to grow quicker autotrophically with methanol, a toxic C1 compound, as the sole substrate. Better ...

Many synthetically useful reactions are catalyzed by cofactor-dependent enzymes. As cofactors represent a major cost factor, methods for efficient cofactor regeneration are required especially for large-scale synthetic applications. In order to generate a novel and efficient host chassis for bioreductions, we engineered the methanol utilization pathway of Pichia pastoris for improved NADH regen...

Duckweed biomass is gasified in a thermochemical-based superstructure to produce gasoline, diesel, and kerosene using a synthesis gas intermediate. The superstructure includes multiple pathways for conversion of the synthesis gas to liquid hydrocarbons via Fischer−Tropsch synthesis or intermediate methanol synthesis. Low-temperature and high-temperature Fischer−Tropsch processes are examined us...

In order to gain a better understanding of the chemistry of methanl-to-hydro-carbon conversion, it is necessary to determine the nature of the primary reaction products. Experiments carried out in this work on H-ZSM-11, using a continuous flow reactor linked to an on-line gas chromatograph demonstrated that ethylene and methane are the primary reaction products. The results obtained using s...

The properties of silver in the oxidative dehydrogenation of methanol were studied in a flow reactor under near industrial conditions. The influences of temperature, concentration of both reactants, gas velocity, space velocity, the form of the silver catalyst and surface composition of the catalyst were studied. A model for the reaction is proposed which is based on the experimental observatio...

Recently, we demonstrated that leaf wounding results in the synthesis of pectin methylesterase (PME), which causes the plant to release methanol into the air. Methanol emitted by a wounded plant increases the accumulation of methanol-inducible gene mRNA and enhances antibacterial resistance as well as cell-to-cell communication, which facilitates virus spreading in neighboring plants. We conclu...

Using surface analysis, simultaneous effects of temperature (260-380ºC) and ethanol concentration (0-1%) on dimethyl ether (DME) selectivity, yields of hydrocarbon and DME, and methanol conversion were investigated in methanol dehydration reaction over γ-Al2O3 catalyst. Methanol conversion and yield of hydrocarbon/DME were found to be significantly affected by temperature and the temperature-et...

Background 2,5-Furandicarboxylic acid is a renewable building block for the production of polyfurandicarboxylates, which are biodegradable polyesters expected to substitute their classical counterparts derived from fossil resources. It may be produced from bio-based 5-hydroxymethylfurfural or 5-methoxymethylfurfural, both obtained by the acidic dehydration of biomass-derived fructose. 5-Methoxy...