Background: Radioguided surgery using 99m-Technetium-methoxyisobutylisonitrile (Tc-MIBI) has been recommended for the surgical treatment of mediastinal parathyroid adenomas. However, high myocardial Tc-MIBI uptake may limit the feasibility of radioguided surgery in aortopulmonary window parathyroid adenoma. Case presentation: Two female patients aged 72 (#1) and 79 years (#2) with primary hyper...

OBJECTIVES In this study, we aimed to analyze the relationship between the diagnostic ability of fused single photon emission computed tomography/ computed tomography (SPECT/CT) images in localization of parathyroid lesions and the size of adenomas or hyperplastic glands. METHODS Five patients with primary hyperparathyroidism (PHPT) and 4 patients with secondary hyperparathyroidism (SHPT) wer...

Abstract Purpose Molecular imaging with 99m Tc-methoxy-isobutyl-isonitrile ( Tc-MIBI, MIBI) has been used in the assessment of thyroid nodules (TNs) for more than two decades. Many studies showed that MIBI is a suitable tool to rule-out malignancy when negative. However, relatively low specificity and accuracy have described, thus, limiting its acceptance clinical practice. Additionally, differ...

A 34 year old woman with malaise, polyuria and nocturia as well as nausea and vomiting referred to perform a thyroid scan due to right thyroid lobe mass. The scan showed a cold nodule in the right thyroid lobe. Serum calcium of 16.9, serum phosphorus of 1.8 and PTH of 1156 were noticed in laboratory tests. Parathyroid scan with 99mTc-MIBI showed no abnormal tracer activity in the nec...

INTRODUCTION Recently, minimally invasive parathyroidectomy (MIP) has been developed and is gaining popularity among surgeons. For this reason, preoperative localization is playing an important role to detect the precise location of the affected gland and to increase the success rate. MATERIAL AND METHODS From June 2007 to June 2011, 56 consecutive patients (11 men and 45 women) with primary ...

parathyroid adenoma involving a single parathyroid gland is the underlying cause of 80-85% of primary hyperparathyroidism (phpt). skeletal system is significantly affected by phpt. brown tumors are known to have affinity for 99mtc-mibi. we report a rare case of phpt presenting with diffuse bony pain, high calcium level and significantly elevated alkaline phosphatase level. 99mtc-pertechnetate/9...

BACKGROUND Primary hyperparathyroidism is a rare disease characterized by excessive secretion of parathyroid hormone from parathyroid adenoma, hyperplasia, or malignancy. The clinical symptoms of the condition are those of hypercalcemia. Although the lesions are commonly located in the neck region, in about 1-2 % of cases, the lesions are ectopically located within the mediastinum, where surgic...

Aim: To evaluate the usefulness of C-methionine PET/CT (MET) in the localization of the parathyroid adenomas and to compare the results with those obtained with the conventional technique in doublephase Tc-sestamibi scintigraphy (MIBI). We evaluated the optimal timing to acquire MET images. Material and methods: A prospective study that included 14 patients (mean age: 65.5 ± 9.7 years) with pri...

Received 11/22/2006; revised 2/14/2007; accepted 2/26/2007. For correspondence or reprints contact: Pei-Wen Wang, M.D., Department of Nuclear Medicine, Chang Gung Memorial Hospital-Kaohsiung Medical Center. 123 Ta-Pei Road, Niao-Sung, Kaohsiung 833, Taiwan, ROC. Tel: (886)7-7317123 ext. 2627, Fax: (886)7-7317123 ext. 2631, E-mail: [email protected] The Tc-MIBI parathyroid imaging is useful for...