Background and Purpose: Candida albicans is a prevalent human fungal pathogen that can cause a wide spectrum of diseases, from superficial mucosal infections to systemic disorders, in patients with impaired immunity. Glabridin is a pyranoisoflavan originally extracted from root extract of Glycyrrhiza glabra. Glabridin can also mediate apoptosis in yeast cells by changing the mitochondrial membr...

A study of the mealybug genus Planococcus Ferris, 1950 (Hemiptera, Coccomorpha, Pseudococcidae) known from China is presented and 12 species are recognised. Of these, camelliae Zhang, sp. nov. described as new to science based on morphology adult female, P. bambusifolii (Takahashi, 1951) recorded for first time. Molecular analyses mitochondrial gene cytochrome c oxidase subunit I (COI) a key in...

Since October 2019, chinch bugs have been detected in large sunken dead patches of St. Augustinegrass (Stenotaphrum secundatum) lawns different locations Lisbon and Setubal districts, Portugal. Based on morphological molecular studies, using mitochondrial Cytochrome C Oxidase subunit I (COI) gene, the collected insects were identified as Blissus insularis (Hemiptera, Heteroptera, Blissidae). Th...

This study reports on the molecular identification of fish species from processed products which had a priori been classified as belonging to 5 important species in Iran for human consumption. DNA barcoding using direct sequencing of an approximately 650bp of mitochondrial Cytochrome oxidase subunit I (COI) gene revealed incorrect labeling of Narrow-barred Spanish mackerel samples. High occurre...

The inner membrane of mitochondria accommodates the oxidative phosphorylation complexes that are composed of subunits encoded and synthesized in two different cellular compartments, with most of the subunits expressed from nuclear DNA. Interestingly, mitochondrial gene expression provides only a handful of proteins that nevertheless represent the catalytic core subunits of the oxidative phospho...

As previously established in yeast, two sequences within mRNAs are responsible for their specific localization to the mitochondrial surface-the region coding for the mitochondrial targeting sequence and the 3'UTR. This phenomenon is conserved in human cells. Therefore, we decided to use mRNA localization as a tool to address to mitochondria, a protein that is not normally imported. For this pur...

The Oenothera mitochondrial genome contains only a gene fragment for ribosomal protein S12 (rps12), while other plants encode a functional gene in the mitochondrion. The complete Oenothera rps12 gene is located in the nucleus. The transit sequence necessary to target this protein to the mitochondrion is encoded by a 5'-extension of the open reading frame. Comparison of the amino acid sequence e...

Epigenetics provides an important layer of information on top of the DNA sequence and is essential for establishing gene expression profiles. Extensive studies have shown that nuclear DNA methylation and histone modifications influence nuclear gene expression. However, it remains unclear whether mitochondrial DNA (mtDNA) undergoes similar epigenetic changes to regulate mitochondrial gene expres...

Tetrastigma rafflesiae (Miq.) Planch. is a climbing plant species that known for its unique relationship with holoparasitic plants of Rafflesiaceae. Knowledge on the mitochondrial genes this may contribute towards development molecular approaches identification. This study aims to identify and characterise from T. genome (mitogenome) assess their potential discriminate different species. Mitoch...