OBJECTIVE To review the safety of simultaneous bilateral posterior cricoarytenoid muscle botulinum toxin injections. DESIGN Retrospective case series review. SETTING Tertiary care academic clinic. PATIENTS Twenty-one patients with abductor spasmodic dysphonia. INTERVENTIONS Patients received 100 simultaneous bilateral posterior cricoarytenoid muscle botulinum toxin injections for isolat...

BACKGROUND Generalized anxiety disorder (GAD) is a prevalent, disabling, and often chronic disorder. With a typical recovery rate of only about 40% with current psychological treatments a better understanding of potential psychophysiological mechanisms is vital. METHODS Since the most discriminative somatic symptom of GAD compared to other anxiety disorders is muscle tension this review quali...

Laser diffraction techniques coupled with simultaneous tension measurements were used to determine the length-tension relation in intact, small (0.5-mm thick, 10-mm wide, 20-25-mm long) bundles of a Limulus (horseshoe crab) striated muscle, the telson levator muscle. This muscle differs from the model vertebrate systems in that the thick filaments are not of a constant length, but shorten from ...

Spasmodic dysphonia (SD) is a rare disease caused by focal dystonia in the laryngeal muscles. The adductor type SD (AdSD), which affects thyroarytenoid (TA) muscle, found 80% of all patients. For them, voice therapy and medication are less effective definitive surgical treatment has not been established yet. Botulinum toxin injection considered gold standard treatment. However, patients require...

This is a report of experiments carried out on the medial gastrocnemius muscle of the anesthetized cat, investigating the effects of eccentric contractions carried out at different muscle lengths on the passive and active length-tension relationships. In one series of experiments, the motor supply to the muscle was divided into three approximately equal parts; in the other, whole muscles were u...

The ability of arterial smooth muscle to generate tension is influenced by muscle length. An unsettled question is whether the length-tension relationship is a simple reflection of the contractile filament overlap, as it is in skeletal muscle. There are several factors that could potentially affect tension generation in arterial smooth muscle; these include stretch-induced myogenic response and...

Type 1 autoimmune hepatitis revealed by a dysphonia related to cricoarytenoid arthritis Sir, Autoimmune hepatitis disease may be accompanied , or revealed by, extra-hepatic (particularly rheumatological) manifestations, in approximately 5% of patients. 1 These manifestations include arth-ralgia, symmetrical non-erosive, non-deforming poly-arthritis, commonly localized on large articulations (kn...

Time under Tension of muscle is one of the variables of strength training that contributes to its adaptation. The present study was conducted the effects of six weeks of resistance training with the varying Time under Tension of muscle on VEGF and endosotene serum levels  in healthy young women. This study was conducted on 20 female students (22.65±2.03years) Subjects were randomly and equally ...