نتایج جستجو برای: mycobacterial
تعداد نتایج: 9511 فیلتر نتایج به سال:
Guidelines for chemotherapy of pulmonary nontuberculous mycobacterial disease--2012 revised version.
In 2008, the Nontuberculous Mycobacteriosis Control Committee of the Japanese Society for Tuberculosis and the Scientifi c Assembly for Infection and Tuberculosis of the Japanese Respiratory Society (hereinafter, the Joint Guidelines Committee) published the Guidelines for chemotherapy of pulmonary nontuberculous mycobacterial disease─2008 interim guidelines 1). In the background, rifabutin (RB...
Most current diagnostic tests for tuberculosis do not reveal the species or strain of pathogen causing pulmonary infection, which can lead to inappropriate treatment regimens and the spread of disease. Here, we report an assay for mycobacterial strain assignment based on genetically conserved mycobacterial sulfatases. We developed a sulfatase-activated probe, 7-hydroxy-9H-(1,3-dichloro-9,9-dime...
Foamy macrophages (FM)s harbor lipid bodies that not only assist mycobacterial persistence within the granulomas but also are sites for intracellular signaling and inflammatory mediators which are essential for mycobacterial pathogenesis. However, molecular mechanisms that regulate intracellular lipid accumulation in FMs during mycobacterial infection are not clear. Here, we report for the firs...
Takeya, Kenji (Kyushu University, Fukuoka, Japan), Kazuhito Hisatsune, and Yasuko Inoue. Mycobacterial cell walls. II. Chemical composition of the "basal layer." J. Bacteriol. 85:24-30. 1963.-Chemical composition of the "basal layer" of the mycobacterial cell wall was determined. The layer contained 35% amino acids, 41.5% reducing sugars (mainly composed of arabinose and galactose), 13.8% amino...
The control of chronic bacterial diseases with high prevalence in areas of endemicity would strongly benefit from availability of postexposure vaccines. The development of these vaccines against mycobacterial infections, such as (para)tuberculosis, is hampered by lack of experience in natural hosts. Paratuberculosis in cattle is both a mycobacterial disease of worldwide importance and a natural...
BACKGROUND Tuberculosis (TB) incidence is decreasing worldwide and eradication is becoming plausible. In low-incidence countries, intervention on migrant populations is considered one of the most important strategies for elimination. However, such measures are inappropriate in European areas where TB is largely endemic, such as Porto in Portugal. We aim to understand transmission chains in Port...
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