Background: Since immunotherapy first emerged as a novel, safe, and effective cancer therapeutic, it was expected to bring new era against cancer. Yet, has fallen short solid tumors, one of the most common causes death, due immune cell’s limitation in penetrating tumor masses. To compensate for traditional therapy, many methods have such antibody drug conjugates (ADC), which challenged by react...

Over the years, polymeric delivery systems have been devoted to overcoming disastrous consequences of using specific medications [1,2]. Among all, stimuli-responsive drug emerged as promising tools for targeting and controlling release therapeutic agents [3-5].

BACKGROUND Iron (Fe) deficiency anemia remains the largest nutritional deficiency disorder worldwide. How the gut acquires iron from nano Fe(III), especially at the apical surface, is incompletely understood. OBJECTIVE We developed a novel Fe supplement consisting of nanoparticulate tartrate-modified Fe(III) poly oxo-hydroxide [here termed nano Fe(III)], which mimics the Fe oxide core of ferr...

Introduction: Recent TEM studies revealed that Fe-Ni metal nano-particles are responsible for the dark “brown” color of olivine in the NWA2737 chassignite, which is interpreted to have formed by reduction of olivine due to heavy shock events [1,2]. Color change of olivine is important to understand the remote sensing data as is the case for space weathering [3,4]. Furthermore, nano-phase Fe par...

Imagine a host of nanoscale DNA robots move autonomously over a microscale DNA nanostructure, each following a programmable route and serving as a nanoparticle and/or an information carrier. The accomplishment of this goal has many applications in nanorobotics, nano-fabrication, nano-electronics, nano-diagnostics/therapeutics, and nano-computing. Recent success in constructing large scale DNA n...

In this work, we present a computational methodology for predicting the change in signal (conductance sensitivity) of a nano-BioFET sensor (a sensor based on a biomolecule binding another biomolecule attached to a nano-wire field effect transistor) upon binding its target molecule. The methodology is a combination of the screening model of surface charge sensors in liquids developed by Brandbyg...