Pasteurella multocida is a gram-negative, non-motile, oxidase positive, catalase indole urease negative, non-spore-forming coccobacillus. Animal bites, scratching, and licking are the most critical risk factors for infections, but it may also occur without any contact. Data about prevalence of these infections in Turkey limited because cases apply to primary healthcare institutions where bacter...

Bacterial infections: By and large PCT levels are elevated in bacterial infections as reported by several studies, but the feature of the response can be different. For example higher peak PCT concentrations are expected in Gram negative as compared to Gram positive infections. Furthermore, differences may also be seen even within the family of Gram negative bacteria: as higher peak PCT concent...

PURPOSE The purpose of this study is to investigate the distribution and antimicrobial susceptibility of pathogenic bacteria in inpatients with pulmonary infection in the neurological intensive care unit (NICU). METHODS A total of 947 sputum specimens of 428 inpatients from May 2007 to May 2008 in the NICU were enrolled in the study, and bacterial identification and antibiotic susceptibility ...

Gram-negative bacterial infections, especially multidrug-resistant (MDR) bacterial infection, are becoming a serious threat to public health. Although it is widely accepted that both appropriate initial empirical therapy and targeted therapy are important, but for patients needing therapy adjustment, few studies have explored whether adjustment strategy based on microbiologic susceptibility tes...

The Toll-dependent defense against Gram-positive bacterial infections in Drosophila is mediated through the peptidoglycan recognition protein SA (PGRP-SA). A mutation termed osiris disrupts the Gram-negative binding protein 1 (GNBP1) gene and leads to compromised survival of mutant flies after Gram-positive infections, but not after fungal or Gram-negative bacterial challenge. Our results demon...

BACKGROUND/AIM Colistin is used as a salvage therapy for multidrug-resistant and extremely drug-resistant gram-negative bacterial infections. Our aim was to evaluate colistin efficiency and toxicity in the treatment of these resistant gram-negative bacterial infections. MATERIALS AND METHODS This is a retrospective study carried out in a tertiary care hospital during 2011-2013. Study data wer...

Nanomaterials are increasingly used to the targeting of gram-positive and gram-negative bacteria as an alternative to antibiotics. Bacterial infections are a major cause of chronic infections and mortality. People requirement for new materials for pathogenic bacteria treatment. It seems that nanomaterial-based strategies can be resolving this problem. In this research, improved antibacterial na...

Amikacin, a new semisynthetic aminoglycoside antibiotic, was administered parenterally to 20 patients suffering from severe Gram-negative bacterial infections. The antibiotic was found to be highly effective in controlling infection. It was well tolerated and no signs of nephro- or otoxicity were observed. The few side-effects which were seen appeared to be dose-related. The recommended 12-hour...