Usually, in make-to-order environments which work only in response to the customer’s orders, manufacturers for maximizing the profits should offer the best price and delivery time for an order considering the existing capacity and the customer’s sensitivity to both the factors. In this paper, an integrated approach for pricing, delivery time setting and scheduling of new arrival orders are prop...

Purpose – To discuss a new parallel algorithmic platform (minlp_machine) for complex mixed-integer non-linear programming (MINLP) problems. Design/methodology/approach – The platform combines features from classical non-linear optimization methodology with novel innovations in computational techniques. The system constructs discrete search zones around noninteger discrete-valued variables at lo...

The paper presents the Mixed-Integer Non-Linear Programming (MINLP) approach to structural optimization. MINLP is a combined discrete/continuous optimization technique, where discrete binary 0-1 variables are defined for optimization of discrete alternatives and continuous variables for optimization of parameters. The MINLP optimization is performed through three steps: i.e. the generation of a...

MOTIVATION Besides their prevalent use for analyzing gene expression, microarrays are an efficient tool for biological, medical and industrial applications due to their ability to assess the presence or absence of biological agents, the targets, in a sample. Given a collection of genetic sequences of targets one faces the challenge of finding short oligonucleotides, the probes, which allow dete...

In addition to their prevalent use for analyzing gene expression, DNA microarrays are an efficient tool for biological, medical, and industrial applications because of their ability to assess the presence or absence of biological agents, the targets, in a sample. Given a collection of genetic sequences of targets one faces the challenge of finding short oligonucleotides, the probes, which allow...

This paper aims to compare a two-echelon and a single-echelon distribution system. A mathematical model for the Single-Echelon Capacitated Vehicle Routing Problem (SE-CVRP) is proposed. This SE-CVRP is the counterpart of Two-Echelon Capacitated Vehicle Routing Problem (2E-CVRP) introduced in the authors’ previous work. The proposed mathematical model is Mixed-Integer Non-Linear Programming (MIN...

abstract in current study, an irrigation examination and acquisition of environmental water in kor-river fields, that is dominated from doroudzan dam to bakhtegan lake, was done by an integrated economy-environmental model. the model was considered by economic, hydrologic and agronomic components. in the economic component, an optimal harvesting of water was done using non-linear programming in...