introduction: [64cu]diacetyl-bis(n4-methylthiosemicarbazone) ([64cu]atsm) is a well-established hypoxia imaging tracer with reproducible production and significant specifity. in this work the high yield production and quality control as well as imaging studies in healthy rabbits is reported. methods: copper-64 produced via the 68zn(p,an)64cu nuclear reaction (30 mev protons at 180 µa) was used...

introduction: in the current study we evaluated the incremental value of lateral pelvic lymphoscintigraphy imaging of endometrial or cervical cancer patients who underwent sentinel node mapping. methods: operable endometrial and cervical cancer patients without clinical or paraclinical evidence of lymph node involvement were included in the study. the day before surgery the patients were sent ...

99mTc-HMPAO labeled platelet (LP) imaging may integrate thrombosis imaging into routine clinical procedures. In the current study, we assessed the feasibility of the use of 99mTc-HMPAO LP for imaging of small clots in an animal model. Thrombosis was induced by application of FeCl3 solution in the distal part of the inferior vena cava (IVC) of a 6100 g anesthetiz...

Radiation detector systems in nuclear medicine imaging A radiation detector system in nuclear medicine imaging is definitely a timely topic or area of research where not many papers are available in the literature of nuclear medicine imaging. Arguably, no single device can detect all kinds of radiation and no one device is useful in all situations. Understanding of the principles of radiation d...

Over the past several years, nuclear imaging modalities such as PET and SPECT have received much attention because they have been instrumental not only in preclinical cancer research but also in nuclear medicine. Yet nuclear imaging is limited by high instrumentation cost and subsequently low availability to basic researchers. Cerenkov radiation, a relativistic physical phenomenon that was disc...

Mitochondria play an important role in energy production for the cell. The proper function of a myocardial cell largely depends on the functional capacity of the mitochondria.  Therefore it is necessary to establish a novel and reliable method for a non-invasive assessment of mitochondrial function and metabolism in humans. Although originally designed for evaluating myocardial perfusion, 99mTc...

Aim: Few nuclear cardiology surveys were published in the literature, mostly from developed countries. The aim of this study is to perform a nuclear cardiology survey in Iran. This may lead to better decision making and programming. Methods and Materials: A questionnaire was sent by mail or e-mail to all nuclear medicine centers in Iran asking for details of nuclear cardiology practice in...