Osyris quadripartita (OQ) Salzm. ex Decne. has been used to treat peptic ulcer disease in Ethiopian folk medicine, but its efficacy has not been validated. The present study was therefore carried out to evaluate the anti-ulcer activity of 80% methanol leaf extract of OQ in rats. The effect of OQ extract on gastric ulcer in rats in pylorus ligation-induced and ethanol-induced models was studied ...

Inflammation of the oral mucosa is a common and debilitating complication of chemotherapy that is preventable and manageable following health advices. Empowering the primary caregiver can be helpful in management of this condition. Aim: To determine the effect of empowering the caregivers on preventing inflammation of oral mucosa in children with cancer undergoing chemotherapy. Methods: This no...

Objective: The present study was undertaken to evaluate the gastroprotective potential of Cajanus cajan seed aqueous extract (CCSE) on experimentally induced gastric ulcer in albino rats. Methods: Preliminary acute toxicity conducted determine oral median lethal dose (LD50). Twenty (20) male rats divided into 5 groups (A-E) 4 animals each were used. Group A (normal control) and B (ulcer model) ...

The clinical features, etiology, and treatment of recurrent aphthous ulcers (RAU) are discussed. Aphthous ulcers are among the most common oral lesions in the general population, with a frequency of up to 25% and three-month recurrence rates as high as 50%. The ulcers, which usually occur on the nonkeratinized oral mucosa, can cause considerable pain and may interfere with eating, speaking, and...

OBJECTIVE Avascular necrosis of bone (AVN) is an important complication of systemic lupus erythematosus (SLE). Corticosteroid therapy has been underlined as a main risk factor for osteonecrosis. However, AVN development in patients who have never received corticosteroid and the absence of AVN in the majority of the patients, who received corticosteroid, propose a role for non-corticosteroid ris...

PURPOSE To assess 1) patient satisfaction of a mucoadhesive biopatch with citrus essential oil and 2) the change in pain severity and the oral health-related quality of life in patients with recurrent aphthous stomatitis. PATIENTS AND METHODS Thirty-seven patients with recurrent aphthous stomatitis participated in the study. Baseline records of personal data, ulcer assessment, visual analog s...

BACKGROUND Recent data suggest a role for high-dose oral proton pump inhibition in ulcer bleeding. AIM To compare the cost-effectiveness of oral high-dose proton pump inhibition to both high-dose intravenous proton pump inhibition and placebo administration. METHODS The model adopted a 30-day time horizon, and focused on patients with ulcer haemorrhage initially treated endoscopically for h...

BACKGROUND Gastrointestinal bleeding is a common problem and its most common etiology is peptic ulcer disease. Ulcer rebleeding is considered a perilous complication for patients. To reduce the rate of rebleeding and to fasten the improvement of patients' general conditions, most emergency departments in Iran use H2-blockers before endoscopic procedures (i.e. intravenous omeprazole is not avail...