Telomeres consist of TTAGGG repeats bound by the shelterin complex and end with a 30 overhang. In humans, telomeres shorten at each cell division, unless telomerase (TERT) is expressed and able to add telomeric repeats. For effective telomere maintenance, the DNA strand complementary to that made by telomerase must be synthesized. Recent studies have discovered a link between different activiti...

This paper investigates the likelihood of corporate insolvency and potential implications debt overhang non-financial corporations induced by economic shock associated with outbreak COVID-19. Based on simple accounting models, it evaluates extent to which firms deplete their equity buffers increase leverage ratios in course COVID-19 crisis. Next, relying regression analysis looking at historica...

This study investigates different cases to obtain optimal Window-to-Wall ratio (WWR) in seven climate conditions based on the Köppen–Geiger classification. The WWR was decided minimum amount of total energy use (total cooling, heating, and lighting use) a building model during complete year. impact overhang automatic blinds were assessed optimization for with integrated control. Moreover, three...

In this study, the resonance-frequency dependence and modal sensitivity of flexural vibration modes overhang/T-shaped microcantilevers to interaction force surface stiffness variations were analysed, a closed-form expression was derived. The Euler–Bernoulli beam theory used develop models, characteristic formula representing cantilever frequencies on overhang dimensions obtained. results derive...