sulfur mustard (sm) is a chemical warfare agent which was widely used in the world war i and more recently during gulf war in the early 1980s'. sm is a strong alkylating agent with known mutagenic and carcinogenic effects but only few studies have been published on its teratogenicity. since sm has been widely used as a chemical weapon by the iraqi regime against the iranian soldiers as well as ...

basal encephalocele is a rare craniofacial anomaly. in the present paper we report a 10-year-old boy presented with cleft palate, congenital nystagmus, and hypertelorism. during preoperative evaluation for cleft palate repair, a pulsatile mass was detected in the pharynx. magnetic resonance imaging showed sphenoethmoidal type of basal encephalocele and agenesis of corpus callosum. neurosurgical...

Introduction: There is a need to more clearly understand the characteristics of breathing patterns in children with cleft palate in the first year of life, as there is little data available to guide current practice. Pierre Robin patients are known to have a higher incidence, however we hypothesised sleep breathing disturbance is not confined to this sub-group of cleft patient. Methods: We cond...

Cleft is a congenital abnormal space or gap in the upper lip, alveolus, palate. This abnormality occurs between 5th and 10th weeks of pregnancy. Clefts are divided into cleft palate, as well lip palate caused by interaction individual genes with certain environmental factors. Mothers’ knowledge about risk factor may promote better health-related behavior their pregnancy increasing understanding...

introduction : surgical repair of cleft palate with a bony bridge may offer some distinct advantages including a lower rate of fistula formation. the goal of this study was to evaluate the feasibility of surgically inducing cleft palate and reconstruction of the cleft with the use of bone morphogenetic protein-2 (bmp-2) in sheep. materials and methods : in the control group (two sheep), the cle...

BACKGROUND Triamcinolone acetonide (TAC) (Kenacort*) is a commonly used synthetic glucocorticoid in today's medical practice. The drug is also a potential agent in inducing cleft palates in rats. This drug has been used to induce cleft palate in the fetus of the pregnant rats to bring out a suitable animal model for human cleft lip and palate. The drug was given intraperitoneally to induce cong...

introduction: reconstruction of intraoral soft tissue defects is important in restoring function and esthetic. in large defects, there will be demand for regional pedicle flaps or free flaps. hard palate separates nasal and oral cavities. due to the small surface area between flap and remaining palate after surgical resections, optimal blood supply of the flaps for hard palate reconstructions a...

The presence of a cleft lip, cleft palate or both, has a huge impact on the life of an individual and their family. Modern management has much to offer these people, revolutionizing appearance and functional defects to a point where they may be difficult to detect. Surgery aims to correct the anatomically obvious cleft lip, augment normal dento-alveolar development and lead to effective palatal...