acyclovir (9-[2-hydroxyethoxymethyl] guanine) is an acyclic nucleoside analogue of guanosine which is a potent and selective antiviral agent. acycloviris converted to the monophosphate by thymidine kinase the virus-specific form of this enzyme and is subsequently converted to the triphosphate by the host cell kinase. acyclovir triphosphate inhibits viral dna-polymerase terminating the chain and...

objectives: patients with hepatitis c virus infection are at high risk of getting hepatitis a virus. hepatitis a virus is an important widespread virus that usually causes more severe medical consequences in patients with chronic liver disease. the purpose of this study was to evaluate prevalence of hepatitis a virus antibody in patients with chronic hcv in isfahan province, iran. methods: a cr...

ulcerative colitis (uc) is one type of inflammatory bowel disease (ibd). herpes viruses have been suggested as possible etiological agents of uc and crohn’s disease (cd). the aim of this study was to investigate the prevalence of herpes simplex virus (hsv), cytomegalovirus (cmv) and epstein-barr virus (ebv) in patients with uc in comparison with healthy subjects by using pcr technique. in this ...

results of 351 patients, 76 patients (group 1) had a strong positive result for salivary occult blood test and 275 patients (group 2) had weak positive or negative test results. significant factors between the groups were obesity, level of ast, alt, ldh, alp, alb, d.bil, t.cho, afp, platelets (plt), iri, homa-ir, current interferon (ifn) treatment and the daily frequency of tooth brushing. betw...

background: the human t-cell lymphotropic virus type i is the first retrovirus idenfied in humans. the virus has been associated with adult t-cell leukemia/lymphoma, human t-lymphotropic virus type i, myelopathy/tropical spasc paraparesis, uveis, arthris, pulmonary lymphocyc alveolis, keratoconjuncvis sicca, and infecous dermas. human t-lymphotropic virus type iis endemic in japan, p...

conclusions the palestinian and israeli official policies to give a booster dose for risk groups like medical students at anti-hbs level below 10 miu/ml should continue to ensure absolute protection. the currently-used vaccine and its time program cleared virus from students believed to have been exposed to the virus during their lifetime. background hepatitis b infection is a global public hea...

introduction: blood derived products have been known as an effective treatment for many years. however, this treatment is not without risk of infections transmission including hepatitis b virus (hbv) and hepatitis c virus (hcv) and human immune-deficiency virus (hiv) in people who received the blood. nevertheless, due to a high risk of blood born diseases through blood transfusion, screening fo...