OBJECTIVES/HYPOTHESIS Routine identification of all four parathyroid glands has been advocated as a means of reducing rates of postoperative hypocalcemia and inadvertent parathyroidectomy. The object of the present study was to investigate whether identification of more parathyroid glands during thyroidectomy performed by capsular dissection technique had any impact on incidence of postoperativ...

Parathyroid hormone (PTH) is an endocrine peptide found exclusively in the parathyroid glands, whereas hormone-related protein (PTHrP) expressed a wide range of tissues and organs exerts endocrine, paracrine, autocrine actions. PTH PTHrP have similar homology, sharing initial 13 amino acid residues at N-terminus binding to same type 1 receptor (PTH1R), which regulates calcium homeostasis. An ab...

OBJECTIVE Primary hyperparathyroidism (PHPT) is often seen in conjunction with an underlying thyroid disorder. Imaging methods that are used to localize the parathyroid adenoma also detect associated thyroid nodules and thyroid cancer. The aim of this study was to detect the rate of thyroid cancer identified while performing parathyroidectomy and thyroidectomy in patients with PHPT. MATERIAL ...

K Nadarasa, A Theodoraki, T R Kurzawinski, R Carpenter, J Bull, T T Chung and W M Drake Department of Endocrinology, St Bartholomew’s Hospital, London, UK, Department of Diabetes and Endocrinology, UCLH NHS Foundation Trust, London, UK, Department of Endocrine Surgery, UCLH NHS Foundation Trust, London, UK and Department of Neurosurgery, The Royal London Hospital, London, UK (K Nadarasa and A T...

Introduction: The purpose of this study is to assess the integrated role of scintigraphy by Tc99m MIBI in diagnosis of parathyroid adenoma and its impacts on the myocardium, and to evaluate whether myocardium perfusion gated SPECT study could be a complementary routine workup for patient with positive parathyroid adenoma on Tc99m MIBI parathyroid scan. Methods: Rest myocardium perfusion gated ...

Introduction: It is not a routine to remove the parathyroid glands during thyroidectomy except when they are ischemic or have malignancy. In this study, the prevalence of parathyroid removal during total thyroidectomy was assessed. Methods: In this case-series study, 53 consecutive patients under total thyroidectomy in two general hospitals during 2013-2014 were enrolled. Serum parathormone va...

introduction: radio-guided parathyroid surgery along with other minimally invasive surgeries constitutes the main surgical treatment procedures for different kinds of hyperparathyroidism.  in this article we have reported our experience of radio-guided parathyroid surgery using tc-99m sestamibi. methods: ten patients with hyperparathyroidism included in our study. twenty mci of tc-99m sestamibi...

Hypercalcemia is found frequently in patients with cancer. Besides the etiology related to the malignancy, other causes should be considered in the differential diagnostic, as primary hyperparathyroidism, granulomatous diseases and the use of thiazide diuretics. We present a case report of a severe hypercalcemia due to a rare association and review the relevant literature. A female patient, 57 ...

A 17-year-old boy with hyperparathyroidism exhibited a large cyst in the left hemi-thorax on his chest X-ray. The cyst was identified as a hydatid cyst. He was referred for biphasic methoxy isobutyl isonitrile (MIBI) parathyroid scan. A discrete ectopic parathyroid was detected in the left upper mediastinum in addition to accumulation of the MIBI tracer in the cyst wall. Using radio-guided occu...